Trial reportCortex; a journal devoted to the study of the nervous system and behavior2018
Prefrontal mediation of the reading network predicts intervention response in dyslexia.
Trial report in Cortex; a journal devoted to the study of the nervous system and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The relation between reading and externalizing behavior: a correlational meta-analysis.Annals of dyslexia · 2024Pooled it
- Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention.Neuroscience and biobehavioral reviews · 2022Pooled it
- Phonics training for English-speaking poor readers.The Cochrane database of systematic reviews · 2018Pooled it
- The interplay between executive function and learning disabilities: Developmental cognitive neuroscience perspectives on reading, math, and ADHD.Developmental cognitive neuroscience · 2026Review
- Uncovering subgroup heterogeneity in dyslexia intervention outcomes using explainable machine learning.NPJ science of learning · 2026Article
- Functional connectivity between the uncinate fasciculus and frontotemporal semantic system supports reading comprehension in adolescents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- An executive-functions-based reading training enhances sensory-motor systems integration during reading fluency in children with dyslexia.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- The reading-attention relationship: Variations in working memory network activity during single word decoding in children with and without dyslexia.Neuropsychologia · 2024Article
- Brain connectivity and academic skills in English learners.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Developmental dyscalculia is not associated with atypical brain activation: A univariate fMRI study of arithmetic, magnitude processing, and visuospatial working memory.Human brain mapping · 2023Article
- Inter-subject correlation during long narratives reveals widespread neural correlates of reading ability.NeuroImage · 2023Article
- Disrupted network interactions serve as a neural marker of dyslexia.Communications biology · 2023Article
- Understanding the interplay between executive functions and reading development: A challenge for researchers and practitioners alike.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023Article
- The Brain's Control Networks in Reading: Insights From Cross-Task Studies of Youth.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023Article
- The behavioral and neurobiological relationships between executive function and reading: A review and preliminary findings.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023Article
- Neural Changes in Children With Residual Speech Sound Disorder After Ultrasound Biofeedback Speech Therapy.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Brain Engagement During a Cognitive Flexibility Task Relates to Academic Performance in English Learners.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023Article
- Exploring Genetic and Neural Risk of Specific Reading Disability within a Nuclear Twin Family Case Study: A Translational Clinical Application.Journal of personalized medicine · 2023Article
- Longitudinal changes in brain activation underlying reading fluency.Human brain mapping · 2023Article
- Researcher-practitioner partnerships and in-school laboratories facilitate translational research in reading.Journal of research in reading · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A primary challenge facing the development of interventions for dyslexia is identifying effective predictors of intervention response. While behavioral literature has identified core cognitive characteristics of response, the distinction of reading versus executive cognitive contributions to response profiles remains unclear, due in part to the difficulty of segregating these constructs using behavioral outputs. In the current study we used functional neuroimaging to piece apart the mechanisms of how/whether executive and reading network relationships are predictive of intervention response. We found that readers who are responsive to intervention have more typical pre-intervention functional interactions between executive and reading systems compared to nonresponsive readers. These findings suggest that intervention response in dyslexia is influenced not only by domain-specific reading regions, but also by contributions from intervening domain-general networks. Our results make a significant gain in identifying predictive bio-markers of outcomes in dyslexia, and have important implications for the development of personalized clinical interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.