Evidence map›Paper›PMID 29458429›Full record

ArticleBMC medical ethics2018

Advance directives as a tool to respect patients' values and preferences: discussion on the case of Alzheimer's disease.

Corinna Porteri

Open access · goldAbstract read
In one paragraph

Article in BMC medical ethics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 46 citations in OpenAlex.

  1. Structuring healthcare advance directives: Evidence from Chinese end-of-life cancer patients' treatment preferences.Health expectations : an international journal of public participation in health care and health policy · 2023
    Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. High-throughput screening for amyloid-Acta pharmaceutica Sinica. B · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Ethical Issues in the Treatment of Late-Stage Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Corinna PorteriBioethics Unit, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Via Pilastroni, 4 - 25125, Brescia, Italy. cporteri@fatebenefratelli.eu.ORCID 0000-0001-7916-0530
Centro San Giovanni di Dio Fatebenefratelli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe proposal of the new criteria for the diagnosis of Alzheimer's disease (AD) based on biomarker data is making possible a diagnosis of AD at the mild cognitive impairment (MCI) or predementia/prodromal- stage. Given the present lack of effective treatments for AD, the opportunity for the individuals to personally take relevant decisions and plan for their future before and if cognitive deterioration occurs is one the main advantages of an early diagnosis. MAIN BODY: Advance directives are largely seen as an effective tool for planning medical care in the event the subject becomes incompetent. Nevertheless, their value has been questioned with regard to people with dementia by scholars who refer to the arguments of personal identity and of patient's changing interests before and after the onset of dementia. In this paper, I discuss the value of advance directives in Alzheimer's disease and other kind of dementia. Despite critics, I argue that advance directives are especially advisable in dementia and provide reasons in favor of their promotion at an early stage of the disease as a valuable tool to respect patients' values and preferences on medical treatment, including participation in research and end of life decisions. I mainly support advance directives that include both decisions regarding health care and the appointment of an attorney in fact.

conclusionI conclude that patients with AD at a prodromal or early stage should be offered the opportunity to execute an advance directive, and that not to honor a demented individual's directive would be an unacceptable form of discrimination towards those patients.

Indexed as

Advance DirectivesAlzheimer DiseaseCognition DisordersDecision MakingMental CompetencyPatient PreferencePatient RightsBiomarkersCognitive DysfunctionDelivery of Health CareDementiaDisease ProgressionDissent and DisputesEarly DiagnosisHumansPersonal AutonomyBiomarkersAdvance directivesAlzheimer’s diseaseAttorney in factDementiaEnd of life decisionsPersonal identity

Identifiers

PMID29458429
PMCPMC5819243
OpenAlexW2794441888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.