ArticleChemistry (Weinheim an der Bergstrasse, Germany)2018
Nucleophilic Substitution in Solution: Activation Strain Analysis of Weak and Strong Solvent Effects.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction: Why Two Is Faster than One.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
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- Dihalogens Binding and Activation by Imidazoline-2-Chalcogenone Model Derivatives: Insight from a Computational Approach.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Coumarin-Triazole-Isatin Hybrids as Selective Butyrylcholinesterase Inhibitors.Molecules (Basel, Switzerland) · 2025Article
- QM/CG-MM: Systematic Embedding of Quantum Mechanical Systems in a Coarse-Grained Environment with Accurate Electrostatics.The journal of physical chemistry. A · 2024Article
- Solvent and solvation effects on reactivities and mechanisms of phospho group transfers from phosphate and phosphinate esters to nucleophiles.Frontiers in chemistry · 2023Review
- Theoretical study of a derivative of chlorophosphine with aliphatic and aromatic Grignard reagents: SRSC advances · 2022Article
- How Solvation Influences the SThe Journal of organic chemistry · 2022Article
- Article
- Facile and Scalable Route to Access Rare Deoxy Amino Sugars for Nonulosonic Acid Aldolase Biosynthesis.Frontiers in chemistry · 2022Article
- Insights into the nucleophilic substitution of pyridine at an unsaturated carbon center.RSC advances · 2021Article
- General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams.ACS catalysis · 2021Article
- Chemical reactivity from an activation strain perspective.Chemical communications (Cambridge, England) · 2021Review
- Reactions of aryl dimethylphosphinothioate esters with anionic oxygen nucleophiles: transition state structure in 70% water-30% ethanol.RSC advances · 2021Article
- A Unified Framework for Understanding Nucleophilicity and Protophilicity in the SChemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- SThe Journal of organic chemistry · 2020Article
- Ambident Nucleophilic Substitution: Understanding Non-HSAB Behavior through Activation Strain and Conceptual DFT Analyses.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Ligand-Mediated Regioselective Rhodium-Catalyzed Benzotriazole-Allene Coupling: Mechanistic Exploration and Quantum Chemical Analysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Understanding chemical reactivity using the activation strain model.Nature protocols · 2020Article
- Dual Activation of Aromatic Diels-Alder Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have quantum chemically studied the effect of various polar and apolar solvents on the shape of the potential energy surface (PES) of a diverse collection of archetypal nucleophilic substitution reactions at carbon, silicon, phosphorus, and arsenic by using density functional theory at the OLYP/TZ2P level. In the gas phase, all our model S
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.