Observational studyCongenital heart disease2018
A multinational observational investigation of illness perceptions and quality of life among patients with a Fontan circulation.
Observational study in Congenital heart disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 32 citations in OpenAlex.
- Quality of Life and Well-Being in Adults With Fontan Physiology: Findings From the Australian and New Zealand Fontan Registry Quality of Life Study.Journal of the American Heart Association · 2024Article
- Long-term patient-reported outcomes following congenital heart surgery in adults.Frontiers in cardiovascular medicine · 2024Article
- The Influence of Illness Perception and Coping on Anxiety in Adults With Congenital Heart Disease.JACC. Advances · 2023Article
- Impact of Family Socioeconomic Status on Health-Related Quality of Life in Children With Critical Congenital Heart Disease.Journal of the American Heart Association · 2019Observational
- Current research status on the psychological situation of adults with congenital heart disease.Cardiovascular diagnosis and therapy · 2018Review
Corrections and comments
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Authors and funding
35 authors at 20 institutions in 15 countries.
Funding
Abstract
objectiveFirst, to compare QOL and illness perceptions between patients with a Fontan circulation and patients with anatomically simple defects (ie, atrial septal defects [ASD] or ventricular septal defects [VSD]). Second, to explore illness perceptions as a mediator of the association between congenital heart disease (CHD) diagnosis and QOL.
designCross-sectional observational study.
settingTwenty-four cardiology centers from 15 countries across five continents. PATIENTS: Four hundred thirty-five adult patients with congenital heart disease (177 Fontan and 258 ASD/VSD) ages 18-83 years. OUTCOME MEASURES: QOL and illness perceptions were assessed by the Satisfaction With Life Scale and the Brief Illness Perceptions Questionnaire, respectively.
resultsPatients with a Fontan circulation reported lower QOL (Wald Z = -3.59, p = <.001) and more negative perceptions of their CHD (Wald Z = -7.66, p < .001) compared with patients with ASD/VSD. After controlling for demographics, anxiety, depressive symptoms, and New York Heart Association functional class, path analyses revealed a significant mediation model, αβ = 0.15, p = .002, 95% CI = 0.06-0.25, such that CHD diagnosis was indirectly related to QOL through illness perceptions.
conclusionsThe Fontan sample's more negative perceptions of CHD were likely a reflection of life with a more complex defect. Illness perceptions appear to account for unique differences in QOL between groups of varying CHD complexity. Psychosocial screening and interventions may be important treatment components for patients with CHD, particularly those with Fontan circulations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.