Evidence map›Paper›PMID 29457335›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Relation of serum uric acid to an exaggerated systolic blood pressure response to exercise testing in men with normotension.

Sae Young Jae, Kanokwan Bunsawat, Yoon-Ho Choi, Yeon Soo Kim, Rhian M Touyz, Jeong Bae Park, Barry A Franklin

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sae Young JaeDepartment of Sport Science, University of Seoul, Seoul, South Korea.ORCID 0000-0003-0358-7866
Kanokwan BunsawatDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Yoon-Ho ChoiCenter for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Yeon Soo KimDepartment of Physical Education, Seoul National University, Seoul, South Korea.
Rhian M TouyzInstitute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, UK.
Jeong Bae ParkDivision of Cardiology, Cheil General Hospital, Dankook University College of Medicine, Seoul, South Korea.ORCID 0000-0002-5623-7010
Barry A FranklinPreventive Cardiology and Cardiac Rehabilitation, William Beaumont Hospital, Royal Oak, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors investigated the hypothesis that high serum uric acid concentrations may be related to an exaggerated systolic blood pressure (SBP) response to maximal exercise testing in men with normotension, independent of potential confounding variables. In 4640 healthy men with normotension who underwent maximal treadmill exercise testing and fasting blood chemistry studies, including serum uric acid concentrations, an exaggerated SBP response, defined as SBP ≥ 210 mm Hg, was detected in 152 men (3.3%). After adjusting for potential confounders, participants in the highest quartile of serum uric acid (>6.6 mg/dL) had a higher odds ratio of demonstrating an exaggerated SBP to maximal exercise (odds ratio, 2.19; 95% confidence interval, 1.24-3.86) compared with participants in the lowest quartile of serum uric acid (<5.1 mg/dL). High serum uric acid concentrations are associated with an exaggerated SBP response to maximal exercise testing in men with normotension, independent of established coronary risk factors.

Indexed as

AdultAgedAged, 80 and overBlood PressureCross-Sectional StudiesExercise TestHealthy VolunteersHumansMaleMiddle AgedOdds RatioUric AcidYoung AdultUric Acidexaggerated systolic blood pressure responseexercise testinguric acid

Identifiers

PMID29457335
PMCPMC8030753

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.