Evidence map›Paper›PMID 29457128›Full record

ArticleACS biomaterials science & engineering2018

Evaluation of Hydrogels Presenting Extracellular Matrix-Derived Adhesion Peptides and Encapsulating Cardiac Progenitor Cells for Cardiac Repair.

Srishti Bhutani, Aline L Y Nachlas, Milton E Brown, Tionne Pete, Christopher T Johnson, Andres J García, Michael E Davis

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Srishti BhutaniWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Aline L Y NachlasWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Milton E BrownWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Tionne PeteWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Christopher T JohnsonWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Andres J GarcíaGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 801 Ferst Drive, Atlanta, Georgia 30313, United States.
Michael E DavisWallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology, 1760 Haygood Drive, W200, Atlanta, Georgia 30322, United States.
Georgia Institute of Technology · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
An automated high-throughput tissue model for screening metastatic effectorsR01CA186134 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J · 2015 to 2019
$3.1M
PEG hydrogels for progenitor cell deliveryR01HL127236 · NHLBI · EMORY UNIVERSITY · PI DAVIS, MICHAEL E · 2016 to 2019
$1.8M
Bacteriophage Presenting Hydrogels to Treat OsteomyelitisF30AR069472 · NIAMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI JOHNSON, CHRISTOPHER THOMAS · 2016 to 2019
$197k
NCI NIH HHS R01 CA186134NHLBI NIH HHS R01 HL127236NIAMS NIH HHS F30 AR069472NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

Cell therapy is an emerging paradigm for the treatment of heart disease. In spite of the exciting and promising preclinical results, the benefits of cell therapy for cardiac repair in patients have been modest at best. Biomaterials-based approaches may overcome the barriers of poor differentiation and retention of transplanted cells. In this study, we prepared and tested hydrogels presenting extracellular matrix (ECM)-derived adhesion peptides as delivery vehicles for c-kit

Indexed as

biomaterialscardiac progenitor cellhydrogelintegrinstem cell

Identifiers

PMID29457128
PMCPMC5812287
OpenAlexW2768373320

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.