Evidence map›Paper›PMID 29456787›Full record

ArticleOxidative medicine and cellular longevity2017

Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome.

Barbara Pietrucha, Edyta Heropolitanska-Pliszka, Mateusz Maciejczyk, Halina Car, Jolanta Sawicka-Powierza, Radosław Motkowski, Joanna Karpinska, Marta Hryniewicka, Anna Zalewska, Malgorzata Pac and 3 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Barbara PietruchaClinical Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Edyta Heropolitanska-PliszkaClinical Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Mateusz MaciejczykDepartment of Experimental Pharmacology, Medical University of Bialystok, Szpitalna 37 Str., 15-295 Bialystok, Poland.ORCID 0000-0001-5609-3187
Halina CarDepartment of Experimental Pharmacology, Medical University of Bialystok, Szpitalna 37 Str., 15-295 Bialystok, Poland.
Jolanta Sawicka-PowierzaDepartment of Family Medicine, Medical University of Bialystok, Bialystok, Poland.
Radosław MotkowskiDepartment of Pediatrics Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, Waszyngtona 17 Str., 15-274 Bialystok, Poland.
Joanna KarpinskaInstitute of Chemistry, University of Bialystok, Bialystok, Poland.ORCID 0000-0002-6100-0691
Marta HryniewickaInstitute of Chemistry, University of Bialystok, Bialystok, Poland.
Anna ZalewskaDepartment of Conservative Dentistry, Medical University of Bialystok, Bialystok, Poland.ORCID 0000-0003-4562-0951
Malgorzata PacClinical Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Beata Wolska-KusnierzClinical Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Ewa BernatowskaClinical Immunology, The Children's Memorial Health Institute, Av. Dzieci Polskich 20, 04-730 Warsaw, Poland.
Bozena MikolucDepartment of Pediatrics Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, Waszyngtona 17 Str., 15-274 Bialystok, Poland.ORCID 0000-0002-8284-6426
Medical University of Białystok · PLChildren's Memorial Health Institute · PLUniversity of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared the antioxidant status and major lipophilic antioxidants in patients with ataxia-telangiectasia (AT) and Nijmegen breakage syndrome (NBS). Total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), and concentrations of coenzyme Q10 (CoQ10) and vitamins A and E were estimated in the plasma of 22 patients with AT, 12 children with NBS, and the healthy controls. In AT patients, TAS (median 261.7

Indexed as

Oxidation-ReductionAdolescentAtaxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsCell Cycle ProteinsChildFemaleHomeostasisHumansMaleNijmegen Breakage SyndromeNuclear ProteinsOxidative StressUbiquinoneVitamin AVitamin EAtaxia Telangiectasia Mutated ProteinsATM protein, humanCell Cycle Proteinscoenzyme Q10NBN protein, humanNuclear ProteinsUbiquinoneVitamin AVitamin E

Identifiers

PMID29456787
PMCPMC5804414
OpenAlexW2777405095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.