ArticleExperimental and therapeutic medicine2018
PRMT1-RBM15 axis regulates megakaryocytic differentiation of human umbilical cord blood CD34
Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- RBM15 in leukemogenesis: an emerging regulator at the interface of RNA biology and hematopoiesis.Trends in cancer · 2026Review
- Silencing AHNAK promotes nasopharyngeal carcinoma progression by upregulating the ANXA2 protein.Cellular oncology (Dordrecht, Netherlands) · 2024Article
- PRMT1 in human neoplasm: cancer biology and potential therapeutic target.Cell communication and signaling : CCS · 2024Review
- Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.The Journal of experimental medicine · 2023Article
- Advances in molecular characterization of pediatric acute megakaryoblastic leukemia not associated with Down syndrome; impact on therapy development.Frontiers in cell and developmental biology · 2023Review
- Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies.Cancers · 2022Review
- RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer.Cancers · 2022Review
- RBM15 condensates modulate mComputational and structural biotechnology journal · 2022Article
- Inhibition of Arginine Methylation Impairs Platelet Function.ACS pharmacology & translational science · 2021Article
- Megakaryocyte progenitor cell function is enhanced upon aging despite the functional decline of aged hematopoietic stem cells.Stem cell reports · 2021Article
- RNA methylation in hematological malignancies and its interactions with other epigenetic modifications.Leukemia · 2021Review
- The role of RNAMolecular therapy. Nucleic acids · 2021Review
- mFrontiers in genetics · 2021Article
- Post-Transcriptional Expression Control in Platelet Biogenesis and Function.International journal of molecular sciences · 2020Review
- RNA-binding proteins in tumor progression.Journal of hematology & oncology · 2020Review
- NMolecular therapy. Nucleic acids · 2020Review
- The regulation, functions and clinical relevance of arginine methylation.Nature reviews. Molecular cell biology · 2019Review
- Protein arginine methyltransferase 1 is required for maintenance of normal adult hematopoiesis.International journal of biological sciences · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein arginine methyltransferase 1 (PRMT1) serves pivotal roles in various cellular processes. However, its role in megakaryocytic differentiation has not been clearly reported. The aim of the present study was to explore the role of the PRMT-RNA binding motif protein 15 (RBM15) axis in human MK differentiation and the feasibility of targeting PRMT1 for leukemia treatment. In the present study, PRMT1 was overexpressed and the RBM15 protein was knocked down in human umbilical cord blood cluster of differentiation (CD)34
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Registered trials
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