Evidence map›Paper›PMID 29456618›Full record

ArticleEcancermedicalscience2018

An unusual presentation of adult T-cell leukemia/lymphoma.

Mohammed Tag-Adeen, Keiichi Hashiguchi, Yuko Akazawa, Ken Ohnita, Sawayama Yasushi, Niino Daisuke, Kazuhiko Nakao

Open access · goldAbstract readCase Reports
In one paragraph

Article in Ecancermedicalscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Oral manifestations of leukemia as part of early diagnosis.Hematology, transfusion and cell therapy
    Review
  3. Evaluation of oral manifestations and head and neck lymphadenopathy in newly diagnosed acute leukemia patients.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Mohammed Tag-AdeenDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Keiichi HashiguchiDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Yuko AkazawaDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Ken OhnitaDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Sawayama YasushiDepartment of Haematology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Niino DaisukeDepartment of Pathology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Kazuhiko NakaoDepartment of Gastroenterology and Hepatology, Nagasaki University Hospital, 1-7-1 Sakamoto, 8528501 Nagasaki-shi, Nagasaki, Japan.
Nagasaki University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult T-cell Leukemia/Lymphoma (ATL) is a rare disease, related to human T-lymphotropic virus-1 (HTLV-1) and presented mainly in adulthood by generalised lymphadenopathy, hepatosplenomegaly, skin lesions and hypercalcaemia, with rare gastrointestinal and/or oral manifestations. We reported this case to raise awareness and demonstrate the therapeutic challenges of this rare disease. A 49-year-old Japanese female presented with skin papules on both forearms, painful mouth ulcers and multiple neck swellings since early February 2017. Initial clinical examination and laboratory investigations were misleading and her condition was diagnosed as candidiasis. Because of un-improvement of the case, a screening upper endoscopy was requested 2 months later and revealed characteristic oropharyngeal ulcers which were biopsied, and its pathologic examination confirmed smouldering type ATL. This case report should raise awareness of doctors and endoscopists about this disease especially in HTLV-1 endemic areas to avoid late diagnosis and help achieve earlier therapeutic decisions.

Indexed as

adult T-Cell leukaemia/lymphomaendoscopic findingshuman T-lymphotropic viruslymphomaoral ulcersoropharyngeal ulcers

Identifiers

PMID29456618
PMCPMC5813913
OpenAlexW2793853212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.