Evidence map›Paper›PMID 29455756›Full record

Trial reportAmerican journal of preventive medicine2018

A Randomized Trial of Weight Change in a National Home Visiting Program.

Debra Haire-Joshu, Cynthia D Schwarz, Karen Steger-May, Christy Lapka, Kenneth Schechtman, Ross C Brownson, Rachel G Tabak

2 registry-linked trialsOpen access · greenAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in American journal of preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01567033 nacompletednot on this map

Translating a Weight Loss Intervention Through a National Home Visiting Program

TypeinterventionalSponsorWashington University School of MedicineRan2012 to 2016Enrolled460ConditionsDiabetes, ObesityArmsPAT Curriculum + Health Information
NCT06773299 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

ENhancing Intergenerational HeAlth in Nigeria: Peripartum as Critical Life StagE for CardioVascular Health

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2028Enrolled1,000ConditionsHypertension in Pregnancy, Hypertension, Obesity and Overweight, Maternal Morbidity and MortalityArmsPAT+HEALTH curriculum - Nigeria
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Interventions to prevent obesity in children aged 2 to 4 years old.The Cochrane database of systematic reviews · 2025
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  4. A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Debra Haire-JoshuCenter for Obesity Prevention and Policy Research, Brown School, Washington University in St. Louis, St. Louis, Missouri; Department of Medicine, Washington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri. Electronic address: djoshu@wustl.edu.
Cynthia D SchwarzCenter for Obesity Prevention and Policy Research, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Karen Steger-MayDepartment of Biostatistics, Washington University School of Medicine, St. Louis, Missouri.
Christy LapkaCenter for Obesity Prevention and Policy Research, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Kenneth SchechtmanDepartment of Biostatistics, Washington University School of Medicine, St. Louis, Missouri.
Ross C BrownsonPrevention Research Center in St. Louis, Brown School, Washington University in St. Louis, St. Louis, Missouri; Department of Surgery and Alvin J. Siteman Cancer Center, Washington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri.
Rachel G TabakPrevention Research Center in St. Louis, Brown School, Washington University in St. Louis, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
Washington University Center for Diabetes Translation Research P30DK092950 · NIDDK · WASHINGTON UNIVERSITY · PI Ross C Brownson, Debra Haire-Joshu · 2011 to 2026
$11.7M
TRANSLATING A WEIGHT LOSS INTERVENTION THROUGH A NATIONAL HOME VISITING PROGRAMR18DK089461 · NIDDK · WASHINGTON UNIVERSITY · PI HAIRE-JOSHU, DEBRA · 2011 to 2015
$3.0M
NIDDK NIH HHS P30 DK056341NIDDK NIH HHS P30 DK092950NIDDK NIH HHS R18 DK089461
6 · The paper itself

Abstract

introductionClinical trials have demonstrated significant impact in reducing weight and incidence of type 2 diabetes mellitus. However, the intensity of these trials limits their scalability to real world settings. The purpose of this study was to embed a lifestyle intervention for overweight and obese mothers within the routine practice of a parent education, home visiting organization.

designPragmatic trial that used a stratified random design. SETTING/

participantsOverweight or obese mothers of preschool children located across St. Louis, Missouri, enrolled in Parents As Teachers, a home visiting organization reaching women and children nationwide.

interventionA lifestyle intervention derived from the Diabetes Prevention Program was embedded within Parents As Teachers entitled Healthy Eating and Active Living Taught at Home (HEALTH).

main outcome measuresOutcomes included the proportion of women that achieved 5% weight loss at 24 months and improvements in clinical and behavioral outcomes at 12 and 24 months. Participants were enrolled from 2012 to 2014 and data analysis began in 2016.

resultsWomen in the usual care versus intervention group were significantly less likely to achieve 5% weight loss at 24 months (11% vs 26%, p=0.01). At 12 months, there was a 2.8-kg difference in weight between groups (p=0.0006), and by 24 months a 4.7-kg difference in weight (3.2 [SD=7.6] kg vs -1.5 [SD=8.3] kg, p=0.002); group differences in waist circumference were also evident by 12 months (2.1 [SD=8.4] cm vs -0.7 [SD=9.8] cm, p=0.04) and 24 months (3.8 [SD=10.6] cm vs -2.5 [SD=9.1] cm, p=0.005), as were improvements in behavioral outcomes. There was no difference in blood pressure between groups.

conclusionsHEALTH achieved modest but clinically significant weight loss outcomes, and reduced weight gain in mothers of young children. The scalability of this embedded intervention offers the potential to reach mothers in Parents As Teachers programs nationally.

trial registrationThis study is registered at www.clinicaltrials.gov NCT01567033.

Indexed as

Life StyleWeight LossAdultBody Mass IndexDiabetes Mellitus, Type 2ExerciseFemaleHumansIncidenceMissouriMothersOverweightProgram EvaluationTeachingTreatment OutcomeUnited States

Identifiers

PMID29455756
PMCPMC5826618
OpenAlexW2791665987

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.