Evidence map›Paper›PMID 29455625›Full record

ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2018

Diarrhea caused by rotavirus A, B, and C in suckling piglets from southern Brazil: molecular detection and histologic and immunohistochemical characterization.

Paula R Almeida, Elis Lorenzetti, Raquel S Cruz, Tatiane T Watanabe, Priscila Zlotowski, Amauri A Alfieri, David Driemeier

Open access · bronzeAbstract read
In one paragraph

Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Diversity of species and genotypes of rotavirus field strains in a diarrhea outbreak in suckling piglets from an unvaccinated pig herd.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  2. Article
  3. Article
  4. The vaccination changed the profile of rotavirus infection with the increase of non-rotavirus A species diagnosis in one-week-old diarrheic piglets.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  5. Review
  6. Article
  7. Diagnostic Approach to Enteric Disorders in Pigs.Animals : an open access journal from MDPI · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Longitudinal study of rotavirus C VP6 genotype I6 in diarrheic piglets up to 1 week old.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paula R AlmeidaSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Elis LorenzettiSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Raquel S CruzSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Tatiane T WatanabeSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Priscila ZlotowskiSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Amauri A AlfieriSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
David DriemeierSetor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil (Almeida, Cruz, Watanabe, Zlotowski, Driemeier).
Universidade Estadual de Londrina · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotavirus (RV) is an important viral pathogen causing diarrhea in piglets and other mammals worldwide. We describe 34 cases from 4 diarrheal outbreaks caused by RV in unvaccinated farrowing units in southern Brazil from 2011 to 2013. We performed autopsy, histologic examinations, bacterial culture, RV immunohistochemistry (IHC), and enteric virus detection through molecular assays for rotavirus A, B, and C, transmissible gastroenteritis virus, porcine epidemic diarrhea virus, sapovirus, norovirus, and kobuvirus. Histologically, villus atrophy (29 of 34) and epithelial vacuolation (27 of 34) occurred in all 4 outbreaks. Cell debris in the lamina propria occurred in 20 cases, mostly from outbreaks A (8 of 11), C (4 of 6), and D (7 of 11). IHC was positive for RV in 21 of 34 samples. RT-PCR was positive for RV in 20 of 30 samples; RV-C was the most frequently detected RV ( n = 17). Kobuvirus was detected in 11 samples, and, in 3 of them, there was single detection of this enteric virus.

Indexed as

AnimalsAnimals, SucklingBrazilDiarrheaDisease OutbreaksFecesImmunohistochemistryPhylogenyRotavirusRotavirus InfectionsSwineSwine DiseasesDiarrheaimmunohistochemistryrotavirusswine

Identifiers

PMID29455625
PMCPMC6505807
OpenAlexW2791087009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.