Evidence map›Paper›PMID 29455619›Full record

ReviewTissue engineering. Part B, Reviews2018

Shaping Cell Fate: Influence of Topographical Substratum Properties on Embryonic Stem Cells.

Sarita Kumari, Steven Vermeulen, Ben van der Veer, Aurélie Carlier, Jan de Boer, Deepa Subramanyam

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. A Tissue Engineering's Guide to Biomimicry.Macromolecular bioscience · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. The extracellular matrix in development.Development (Cambridge, England) · 2020
    Review
  8. High-Aspect-Ratio Nanostructured Surfaces as Biological Metamaterials.Advanced materials (Deerfield Beach, Fla.) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarita Kumari1 National Center for Cell Science, SP Pune University , Pune, India .
Steven Vermeulen2 Laboratory for Cell Biology-Inspired Tissue Engineering, MERLN Institute, University of Maastricht , Maastricht, The Netherlands .
Ben van der Veer2 Laboratory for Cell Biology-Inspired Tissue Engineering, MERLN Institute, University of Maastricht , Maastricht, The Netherlands .
Aurélie Carlier2 Laboratory for Cell Biology-Inspired Tissue Engineering, MERLN Institute, University of Maastricht , Maastricht, The Netherlands .
Jan de Boer2 Laboratory for Cell Biology-Inspired Tissue Engineering, MERLN Institute, University of Maastricht , Maastricht, The Netherlands .
Deepa Subramanyam1 National Center for Cell Science, SP Pune University , Pune, India .

Funding

DBT-Wellcome Trust India Alliance IA/I/12/1/500507
6 · The paper itself

Abstract

Development of multicellular organisms is a highly orchestrated process, with cells responding to factors and features present in the extracellular milieu. Changes in the surrounding environment help decide the fate of cells at various stages of development. This review highlights recent research that details the effects of mechanical properties of the surrounding environment and extracellular matrix and the underlying molecular mechanisms that regulate the behavior of embryonic stem cells (ESCs). In this study, we review the role of mechanical properties during embryogenesis and discuss the effect of engineered microtopographies on ESC pluripotency.

Indexed as

Stem Cell NicheAnimalsEmbryonic DevelopmentExtracellular MatrixHuman Embryonic Stem CellsHumansTissue Engineeringembryonic stem cellsextracellular matrixpluripotencysubstratum

Identifiers

PMID29455619
PMCPMC7116060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.