Evidence map›Paper›PMID 29455573›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

A CREB-mediated increase in miRNA let-7f during prolonged β-agonist exposure: a novel mechanism of β

Donghwa Kim, Soomin Cho, Jung A Woo, Stephen B Liggett

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Cell-cell communication: new insights and clinical implications.Signal transduction and targeted therapy · 2024
    Review
  7. miRNAs as Modern Biomarkers in Asthma Therapy.International journal of molecular sciences · 2023
    Review
  8. Noncoding RNAs in asthmatic airway smooth muscle cells.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  9. Article
  10. Article
  11. [Expression of CREB in children with recurrent wheezing and its effect on ORMDL3 gene expression].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Donghwa KimCenter for Personalized Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Soomin ChoCenter for Personalized Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Jung A WooDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA; and.
Stephen B LiggettDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA; and.
University of South Florida · US

Funding

Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
Molecular properties of B-adrenergic receptors in AsthmaR37HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 2002 to 2012
$3.2M
MOLECULAR PROPERTIES OF B-ADRENERGIC RECEPTORS IN ASTHMAR01HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 1990 to 2018
$1.3M
Molecular properties of B-adrenergic receptors in AsthmaR56HL045967 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIGGETT, STEPHEN B · 2015 to 2015
$374k
NHLBI NIH HHS P01 HL114471NHLBI NIH HHS R01 HL045967NHLBI NIH HHS R37 HL045967NHLBI NIH HHS R56 HL045967
6 · The paper itself

Abstract

β

Indexed as

Adrenergic beta-2 Receptor AgonistsAsthmaCell LineCyclic AMP Response Element-Binding ProteinDown-RegulationHumansLungMicroRNAsMuscle, SmoothReceptors, Adrenergic, beta-2Adrenergic beta-2 Receptor AgonistsCyclic AMP Response Element-Binding ProteinMicroRNAsmirnlet7 microRNA, humanReceptors, Adrenergic, beta-2asthmaG proteinmicroRNAtachyphylaxis

Identifiers

PMID29455573
PMCPMC5998966
OpenAlexW2789803223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.