Evidence map›Paper›PMID 29455419›Full record

ArticleParasitology research2018

Further aspects of Toxoplasma gondii elimination in the presence of metals.

Laís Pessanha de Carvalho, Edésio José Tenório de Melo

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laís Pessanha de CarvalhoLaboratory of Tissue and Cell Biology, State University of North Fluminense-Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, 28013-602, Brazil.
Edésio José Tenório de MeloLaboratory of Tissue and Cell Biology, State University of North Fluminense-Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro, 28013-602, Brazil. ejtm1202@gmail.com.
State University of Norte Fluminense · BR

Funding

FAPERJ E-26/010.002612/2014
6 · The paper itself

Abstract

Toxoplasma gondii, the etiological agent of toxoplasmosis, infects nucleated cells and then resides and multiplies within a parasitophorous vacuole. For this purpose, the parasite secretes many virulence factors for the purpose of invading and subverting the host microbicidal defenses in order to facilitate its survival in the intracellular milieu. Essential metals are structural components of proteins and enzymes or cofactors of enzymatic reactions responsible for these parasitic survival mechanisms. However, an excess of non-essential or essential metals can lead to parasite death. Thus, infected host cells were incubated with 20 μM ZnCl

Indexed as

AnimalsAutophagyBiological TransportCadmium ChlorideCell LineChloridesHost-Parasite InteractionsLysosomesMacaca mulattaMercuric ChlorideMitochondriaNucleic Acid DenaturationToxoplasmaVacuolesVirulence FactorsZinc CompoundsCadmium ChlorideChloridesMercuric ChlorideVirulence Factorszinc chlorideZinc CompoundsCadmiumEssential metalMercuryNonessential metalsToxoplasma gondiiZinc

Identifiers

PMID29455419
OpenAlexW2788538572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.