Evidence map›Paper›PMID 29455369›Full record

ReviewNeurosurgical review2019

Intradural spinal tumors in adults-update on management and outcome.

Malte Ottenhausen, Georgios Ntoulias, Imithri Bodhinayake, Finn-Hannes Ruppert, Stefan Schreiber, Annette Förschler, John A Boockvar, Andreas Jödicke

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurosurgical review, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  3. Risk factors analysis for spinal deformity following resection of intradural spinal cord tumors from posterior approach: systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Malte OttenhausenDepartment of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany.
Georgios NtouliasDepartment of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany.
Imithri BodhinayakeThe Feinstein Institute for Medical Research, Manhasset, USA.
Finn-Hannes RuppertDepartment of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany.
Stefan SchreiberDepartment of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany.
Annette FörschlerDepartment of Radiology and Neuroradiology, Schlossparkklinik, Berlin, Germany.
John A BoockvarDepartment of Neurosurgery, Lenox Hill Hospital, New York, USA.
Andreas JödickeDepartment of Neurosurgery, Vivantes Klinikum Neukölln, Berlin, Germany. Andreas.Joedicke@vivantes.de.ORCID http://orcid.org/0000-0003-4584-4875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among spinal tumors that occur intradurally, meningiomas, nerve sheath tumors, ependymomas, and astrocytomas are the most common. While a spinal MRI is the state of the art to diagnose intradural spinal tumors, in some cases CT scans, angiography, CSF analyses, and neurophysiological examination can be valuable. The management of these lesions depends not only on the histopathological diagnosis but also on the clinical presentation and the anatomical location, allowing either radical resection as with most extramedullary lesions or less invasive strategies as with intramedullary lesions. Although intramedullary lesions are rare and sometimes difficult to manage, well-planned treatment can achieve excellent outcome without treatment-related deficits. Technical advances in imaging, neuromonitoring, minimally invasive approaches, and radiotherapy have improved the outcome of intradural spinal tumors. However, the outcome in malignant intramedullary tumors remains poor. While surgery is the mainstay treatment for many of these lesions, radiation and chemotherapy are of growing importance in recurrent and multilocular disease. We reviewed the literature on this topic to provide an overview of spinal cord tumors, treatment strategies, and outcomes. Typical cases of extra- and intramedullary tumors are presented to illustrate management options and outcomes.

Indexed as

AdultHumansMagnetic Resonance ImagingSpinal Cord NeoplasmsSpinal NeoplasmsTomography, X-Ray ComputedAstrocytomaDumbbell tumorEpendymomaIntraduralIntramedullaryMeningiomaNeurofibromaSchwannomaSpinal

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.