Evidence map›Paper›PMID 29455342›Full record

ArticleCell stress & chaperones2018

Pre-protective effects of dietary chitosan supplementation against oxidative stress induced by diquat in weaned piglets.

Y Q Xu, Y Y Xing, Z Q Wang, S M Yan, B L Shi

Open access · greenAbstract read
In one paragraph

Article in Cell stress & chaperones, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Risk factors for death in patients with acute diquat poisoning.World journal of emergency medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Y Q XuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Y Y XingCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Z Q WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
S M YanCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China.
B L ShiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, 010018, China. shibinlin@yeah.net.
Inner Mongolia Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protective effects of chitosan (CS) supplementations on oxidative stress induced by diquat in weaned piglets were investigated. A total of 36 crossbreed piglets with an average live body weight (BW) of 8.80 ± 0.53 kg were weaned at 28 ± 2 days and randomly divided into six dietary treatments (n = 6): control (basal diet), negative control (10 mg diquat/kg BW injected to piglets fed with basal diet), and basal diet treatments containing either 250, 500, 1000, or 2000 mg/kg of CS administered to piglets injected with 10 mg diquat/kg BW. The experiment conducted for 21 days which consisted of pre-starter period (14 days) and starter period (7 days). BW, feed intake, and fecal consistency were monitored. Blood samples were collected to determine antioxidative and immune parameters. CS supplementation improved the growth performance and decreased fecal score of piglets from days 1 to 14. Diquat also induced oxidative stress and inflammatory responses by decreasing the activities of antioxidant and regulating cytokines. But dietary CS alleviated these negative effects induced by diquat that showed decreasing serum concentrations of pro-inflammatory cytokines but increasing activities of antioxidant enzymes and anti-inflammatory cytokines. Results indicated that CS attenuated the oxidative stress of piglets caused by diquat injection.

Indexed as

Dietary SupplementsWeaningAnimalsAntioxidantsBiomarkersChitosanDiarrheaDiquatFecesFemaleImmunoglobulinsMaleMalondialdehydeOxidative StressProtective AgentsSwineAntioxidantsBiomarkersChitosanDiquatImmunoglobulinsMalondialdehydeProtective AgentsAntioxidant capacityChitosanCytokineDiarrheaGrowth performance

Identifiers

PMID29455342
PMCPMC6045548
OpenAlexW2792014897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.