Evidence map›Paper›PMID 29455334›Full record

ArticleProbiotics and antimicrobial proteins2019

Septicemia from Lactobacillus rhamnosus GG, from a Probiotic Enriched Yogurt, in a Patient with Autologous Stem Cell Transplantation.

Satoshi Koyama, Hiroyuki Fujita, Takeshi Shimosato, Aki Kamijo, Yasufumi Ishiyama, Eri Yamamoto, Yoshimi Ishii, Yukako Hattori, Maki Hagihara, Etsuko Yamazaki and 3 more

Abstract readCase Reports
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 61 citations in OpenAlex.

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  15. Microorganisms · 2023
    Review
  16. Current research in food science · 2023
    Article
  17. Review
  18. Bacteraemia Caused by Probiotic Strains ofPathogens (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Satoshi KoyamaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Hiroyuki FujitaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan. fujitah@nanbu.saiseikai.or.jp.ORCID http://orcid.org/0000-0002-6084-6863
Takeshi ShimosatoResearch Center for Fungal and Microbial Dynamism, Shinshu University, Kamiina, Japan.
Aki KamijoDepartment of Transfusion, Yokohama City University Hospital, Yokohama, Japan.
Yasufumi IshiyamaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Eri YamamotoDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Yoshimi IshiiDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Yukako HattoriDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Maki HagiharaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Etsuko YamazakiDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Naoto TomitaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Hideaki NakajimaDepartment of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Yokohama Cooperative Study Group for Hematology (YACHT)
Kanagawa Prefectural Hospital Organization · JPShinshu University · JPSt. Marianna University School of Medicine · JPYokohama City University · JPYokohama City University Hospital · JPYokohama City University Medical Center · JPFujisawa City Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic-rich foods are consumed without much restriction. We report here, a case of septic shock caused by yogurt derived Lactobacillus species in a 54-year-old male patient with acute promyelocytic leukemia, in second complete remission, and who was an autologous stem cell transplantation recipient. He received high dose chemotherapy and autologous peripheral blood stem cell transplantation. He ingested commercially available probiotic-enriched yogurt because of severe diarrhea. One week later, he developed septic shock, and the pathogen was determined by strain-specific PCR analysis as Lactobacillus rhamnosus GG (ATCC 53103), which was found to be identical with the strain in the yogurt he consumed. Thus, because even low virulent Lactobacilli in the probiotic products can be pathogenic in the compromised hosts, ingestion of such products should be considered with caution in neutropenic patients with severe diarrhea, such as stem cell transplantation recipients.

Indexed as

Hematopoietic Stem Cell TransplantationHumansLacticaseibacillus rhamnosusLeukemiaMaleMiddle AgedProbioticsSepsisTransplantation, AutologousYogurtLactobacillusLeukemiaProbiotic yogurt, bacteremiaStem cell transplantation

Identifiers

PMID29455334
OpenAlexW2789558989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.