Evidence map›Paper›PMID 29454367›Full record

ArticleVirology journal2018

Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation.

Cyprien Beraud, Morgane Lemaire, Danielle Perez Bercoff

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cyprien BeraudDepartment of Infection and Immunity, Molecular Signaling and Virus-Host Interactions group, Luxembourg Institute of Health, 29, rue Henri Koch, L-4354, Esch-sur-Alzette, Luxembourg.
Morgane LemaireDepartment of Infection and Immunity, Molecular Signaling and Virus-Host Interactions group, Luxembourg Institute of Health, 29, rue Henri Koch, L-4354, Esch-sur-Alzette, Luxembourg.
Danielle Perez BercoffDepartment of Infection and Immunity, Molecular Signaling and Virus-Host Interactions group, Luxembourg Institute of Health, 29, rue Henri Koch, L-4354, Esch-sur-Alzette, Luxembourg. danielle.perezbercoff@lih.lu.ORCID 0000-0003-4415-0150
Luxembourg Institute of Health · LU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane. It has also been reported to promote transcription from the viral LTR both directly and indirectly. Noticeably, the HIV-1 and SIV

Indexed as

Protein Interaction Domains and Motifsenv Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHumansNF-kappa BProtein BindingT-Lymphocyte SubsetsVirus Replicationenv Gene Products, Human Immunodeficiency VirusNF-kappa BEnv cytoplasmic domainHIV-1NF-κBTranscription

Identifiers

PMID29454367
PMCPMC5816530
OpenAlexW2805097924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.