Evidence map›Paper›PMID 29454325›Full record

ArticleBMC public health2018

Latent tuberculosis infection and associated risk indicators in pastoral communities in southern Ethiopia: a community based cross-sectional study.

Takele Teklu, Mengistu Legesse, Girmay Medhin, Aboma Zewude, Mahlet Chanyalew, Martha Zewdie, Biniam Wondale, Milkessa Haile-Mariam, Rembert Pieper, Gobena Ameni

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Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes.Current topics in microbiology and immunology · 2023
    Review
  7. Possible sex difference in latent tuberculosis infection risk among close tuberculosis contacts.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Effect of pregnancy and HIV infection on detection of latent TB infection by Tuberculin Skin Test and QuantiFERON-TB Gold In-Tube assay among women living in a high TB and HIV burden setting.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  15. Article
  16. Sex differences in tuberculosis.Seminars in immunopathology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takele TekluAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia. takeleteklua@gmail.com.
Mengistu LegesseAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Girmay MedhinAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Aboma ZewudeAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Mahlet ChanyalewAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Martha ZewdieArmauer Hansen Research Institute, AHRI, PO Box 1005, Addis Ababa, Ethiopia.
Biniam WondaleAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Milkessa Haile-MariamAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.
Rembert PieperJ. Craig Venter Institute, Rockville, MD, USA.
Gobena AmeniAklilu Lemma Institute of Pathobiology (ALIPB), Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia.

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
Systems Biology for Molecular Analysis of Tuberculosis in EthiopiaU01HG007472 · NHGRI · ADDIS ABABA UNIVERSITY · PI AMENI, GOBENA · 2013 to 2016
$1.2M
FIC NIH HHS D43 TW009127NHGRI NIH HHS U01 HG007472
6 · The paper itself

Abstract

backgroundResearch pertaining to the community-based prevalence of latent tuberculosis infection (LTBI) is important to understand the magnitude of this infection. This study was conducted to estimate LTBI prevalence and to identify associated risk factors in the Omo Zone of Southern Ethiopia.

methodsA community-based cross-sectional study was conducted in six South Omo districts from May 2015 to February 2016. The sample size was allocated to the study districts proportional to their population sizes. Participants were selected using a multi-stage sampling approach. A total of 497 adult pastoralists were recruited. Blood samples were collected from the study participants and screened for LTBI using a U.S. Food and Drug Administration approved interferon-gamma release assay (IGRA). Logistic regression was used to model the likelihood of LTBI occurrence and to identify risk factors associated with LTBI.

resultsThe prevalence of LTBI was 50.5% (95% CI: 46%, 55%) with no significant gender difference (49.8% among males versus 51.2% among females; Chi-square (χ

conclusionsA high prevalence of LTBI in the South Omo Zone raises the concern that elimination of TB in the pastoral communities of the region might be difficult. Screening for and testing individuals infected with TB, independent of symptoms, may be an effective way to minimize the risk of disease spread.

Indexed as

AdolescentAdultAgedAged, 80 and overAnimal HusbandryCross-Sectional StudiesEthiopiaFamily CharacteristicsFemaleHumansLatent TuberculosisMaleMiddle AgedPrevalenceRisk FactorsYoung AdultEthiopiaIGRALTBIPrevalenceSouth Omo

Identifiers

PMID29454325
PMCPMC5816385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.