Evidence map›Paper›PMID 29454307›Full record

SynthesisBMC geriatrics2018

Association between residual teeth number in later life and incidence of dementia: A systematic review and meta-analysis.

Bumjo Oh, Dong-Hun Han, Kyu-Tae Han, Xibei Liu, Johnson Ukken, Carina Chang, Kiki Dounis, Ji Won Yoo

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC geriatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bumjo OhDepartment of Family Medicine, SMG-SNG Boramae Medical Center, Seoul, South Korea.
Dong-Hun HanDepartment of Preventive & Social Dentistry, Seoul National University School of Dentistry, Seoul, South Korea.
Kyu-Tae HanResearch and Analysis Team, Ilsan National Health Insurance Hospital, Gyeonggi-do, Goyang-si, South Korea.
Xibei LiuDepartment of Medicine, University of Arizona College of Medicine, Tucson, AZ, USA.
Johnson UkkenUniversity of Nevada School of Medicine, Reno, Nevada, USA.
Carina ChangUniversity of Nevada School of Medicine, Reno, Nevada, USA.
Kiki DounisVeterans Affairs Southern Nevada Healthcare System, North Las Vegas, Nevada, USA.
Ji Won YooDepartmemnt of Internal Medicine, University of Nevada Las Vegas School of Medicine, 1701 W Charleston Blvd. #230, Las Vegas, Nevada, 89102, USA. ji.yoo@unlv.edu.

Funding

University of Nevada, Las Vegas 16-016
6 · The paper itself

Abstract

backgroundIt has been suggested that tooth loss in later life might increase dementia incidence. The objective of this analysis is to systematically review the current evidence on the relationship between the number of remaining teeth and dementia occurrence in later life.

methodsA search of multiple databases of scientific literature was conducted with relevant parameters for articles published up to March 25th, 2017. Multiple cohort studies that reported the incidence of dementia and residual teeth in later life were found with observation periods ranging from 2.4 to 32 years. Random-effects pooled odds ratios (OR) and 95% confidence intervals (CI) were estimated to examine whether high residual tooth number in later life was associated with a decreased risk of dementia. Heterogeneity was measured by I

resultsThe literature search initially yielded 419 articles and 11 studies (aged 52 to 75 at study enrollment, n = 28,894) were finally included for analysis. Compared to the low residual teeth number group, the high residual teeth number group was associated with a decreased risk of dementia by approximately 50% (pooled OR = 0.483; 95% CI 0.315 to 0.740; p < 0.001; I

conclusionDespite limited scientific strength, the current meta-analysis reported that a higher number of residual teeth was associated with having a lower risk of dementia occurrence in later life.

Indexed as

AgedAged, 80 and overAge FactorsAgingDementiaHumansIncidenceMiddle AgedTooth LossDementia[MeSH terms]: ElderlyMeta-analysisTeeth

Identifiers

PMID29454307
PMCPMC5816354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.