Evidence map›Paper›PMID 29453860›Full record

SynthesisMycoses2018

Fungal infections in patients with inflammatory bowel disease: A systematic review.

George A Stamatiades, Petros Ioannou, George Petrikkos, Constantinos Tsioutis

Abstract readSystematic Review
In one paragraph

Synthesis in Mycoses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Stool multiplex PCR assay versus conventional stool tests for detecting gastrointestinal infection as a cause for flare of inflammatory bowel disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  4. Fungal Pancolitis in an Immunocompetent Patient: A Case Report.Middle East journal of digestive diseases · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Role of fungus in inflammatory bowel disease: The butterfly effect?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
  12. Fungemia byPathogens (Basel, Switzerland) · 2024
    Review
  13. Raising the bar in ulcerative colitis management.Therapeutic advances in gastroenterology · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Bile Acid Regulates the Colonization and Dissemination ofJournal of fungi (Basel, Switzerland) · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

George A StamatiadesInfectious Diseases Working Group, Society of Junior Doctors, Athens, Greece.ORCID http://orcid.org/0000-0002-9407-6326
Petros IoannouInfectious Diseases Working Group, Society of Junior Doctors, Athens, Greece.ORCID http://orcid.org/0000-0003-1082-5674
George PetrikkosSchool of Medicine, European University of Cyprus, Nicosia, Cyprus.
Constantinos TsioutisInfectious Diseases Working Group, Society of Junior Doctors, Athens, Greece.ORCID http://orcid.org/0000-0002-7865-8529

Funding

TRAINING GRANT IN ACADEMIC ENDOCRINOLOGYT32DK007529 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI Ursula B. Kaiser, Anand Vaidya · 1986 to 2026
$6.3M
NIDDK NIH HHS T32 DK007529
6 · The paper itself

Abstract

backgroundDespite reports of fungal infections in patients with inflammatory bowel disease (IBD), their clinical and microbiological characteristics remain unknown.

objectivesThe aim of this systematic review was to examine all available evidence regarding fungal infections in patients with IBD.

methodsSystematic search of PubMed (through 27 May 2017) for studies providing data on clinical, microbiological, treatment and outcome data of fungal infections in patients with IBD. The primary study outcome was to record the most common fungal species in patients with IBD. Secondary outcomes were classified into 3 categories: (i) characteristics of fungal infections; (ii) data on IBD and (iii) treatment and outcomes of fungal infections in patients with IBD.

resultsFourteen studies with data on 1524 patients were included in final analysis. The most common fungal infections in patients with IBD were caused by Candida species (903 infections); the most commonly reported site of Candida infection was the gastrointestinal tract. Available evidence shows that most fungal infections occur within 12 months of IBD treatment and within 6 months when anti-TNFa agents are used.

conclusionsThis systematic review thoroughly describes fungal infections in patients with IBD and provides important information for the early detection and management of these infections.

Indexed as

AdultCandidaChildColitis, UlcerativeCrohn DiseaseFemaleGastrointestinal TractHumansInflammatory Bowel DiseasesMaleMycosesRandomized Controlled Trials as TopicRisk FactorsCrohn'sfungal infectioninflammatory bowel diseaseopportunisticsystematic reviewulcerative colitis

Identifiers

PMID29453860
PMCPMC5980782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.