Evidence map›Paper›PMID 29453663›Full record

ArticlePlanta2018

The rice "fruit-weight 2.2-like" gene family member OsFWL4 is involved in the translocation of cadmium from roots to shoots.

Wentao Xiong, Peng Wang, Tianze Yan, Baobao Cao, Jun Xu, Defang Liu, Meizhong Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Genome-Wide Identification of thePlants (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Research Progress onBiology · 2025
    Review
  5. Article
  6. Review
  7. Genome-Wide Analyses ofInternational journal of molecular sciences · 2023
    Article
  8. Review
  9. Nucleotide polymorphisms of the maizeFrontiers in genetics · 2022
    Article
  10. Mutation inInternational journal of molecular sciences · 2021
    Article
  11. Article
  12. Targeted Mutagenesis of the RiceInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wentao XiongNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Peng WangNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Tianze YanNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Baobao CaoNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Jun XuNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Defang LiuNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Meizhong LuoNational Key Laboratory of Crop Genetic Improvement and College of Life Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China. mzluo@mail.hzau.edu.cn.

Funding

National Natural Science Foundation of China (CN) 31671268
6 · The paper itself

Abstract

MAIN

conclusionHeterogeneous expression of the rice genes "fruit-weight 2.2-like" (OsFWL) affects Cd resistance in yeast, and OsFWL4 mediates the translocation of Cd from roots to shoots. Cadmium (Cd) induces chronic and toxic effects in humans. In a previous study (Xu et al. in Planta 238:643-655, 2013), we cloned the rice genes, designated OsFWL1-8, homologous to the tomato fruit-weight 2.2. Here, we show that expression of genes OsFWL3-7 in yeast confers resistance to Cd. The Cd contents of OsFWL3-, -4-, -6- and -7-transformed Cd(II)-sensitive yeast mutant ycf1 cells were strongly decreased compared with those of empty vector, with the strongest resistance to Cd observed in cells expressing OsFWL4. Evaluation of truncated and site-directed mutation derivatives revealed that the CCXXG motifs near the second transmembrane region of OsFWL4 are involved in Cd resistance in yeast. Real-time PCR analysis showed that OsFWL4 expression was induced by CdCl

Indexed as

Blotting, WesternCadmiumCadmium ChlorideGene Knockdown TechniquesGenes, PlantOryzaPlant ProteinsPlant RootsPlant ShootsReal-Time Polymerase Chain ReactionTwo-Hybrid System TechniquesCadmiumCadmium ChloridePlant ProteinsCCXXG motifCd resistanceCd translocationHeavy metalsOsFWL

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.