Evidence map›Paper›PMID 29453527›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2018

Effects of 4,9-anhydrotetrodotoxin on voltage-gated Na

Kohei Takahara, Tadashi Yamamoto, Keiichiro Uchida, Hai-Lei Zhu, Atsushi Shibata, Tetsuichiro Inai, Mitsuru Noguchi, Mari Yotsu-Yamashita, Noriyoshi Teramoto

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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kohei TakaharaDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Tadashi YamamotoDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Keiichiro UchidaDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Hai-Lei ZhuDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Atsushi ShibataDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Tetsuichiro InaiDepartment of Morphological Biology, Division of Biomedical Sciences, Fukuoka Dental College, Fukuoka, 814-0193, Japan.
Mitsuru NoguchiDepartment of Urology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan.
Mari Yotsu-YamashitaLaboratory of Bioorganic Chemistry of Natural Products, Graduate School of Agricultural Science, Tohoku University, Sendai, 981-8555, Japan.
Noriyoshi TeramotoDepartment of Pharmacology, Faculty of Medicine, Saga University, Saga, 849-8501, Japan. noritera@cc.saga-u.ac.jp.
Saga University · JPFukuoka Dental College · JPTohoku University · JP

Funding

Japan Society for the Promotion of Science 16K12913Japan Society for the Promotion of Science 16K19020Japan Society for the Promotion of Science 17H02111
6 · The paper itself

Abstract

Molecular investigations were performed in order to determine the major characteristics of voltage-gated Na

Indexed as

AnimalsCerebrumHEK293 CellsHumansMaleMice, Inbred BALB CMyocytes, Smooth MuscleProtein SubunitsRecombinant ProteinsSodium Channel BlockersTetrodotoxinVas DeferensVoltage-Gated Sodium ChannelsanhydrotetrodotoxinProtein SubunitsRecombinant ProteinsSodium Channel BlockersTetrodotoxinVoltage-Gated Sodium Channels4,9-AnhydrotetrodotoxinMouse vas deferensNaV1.6 channelsSmooth muscle-type NaVβ1-subunit

Identifiers

PMID29453527
OpenAlexW2788993947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.