Evidence map›Paper›PMID 29453444›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018

Positive regulation of raphe serotonin neurons by serotonin 2B receptors.

Arnauld Belmer, Emily Quentin, Silvina L Diaz, Bruno P Guiard, Sebastian P Fernandez, Stéphane Doly, Sophie M Banas, Pothitos M Pitychoutis, Imane Moutkine, Aude Muzerelle and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. 5-HTiScience · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. The Roles of Serotonin in Neuropsychiatric Disorders.Cellular and molecular neurobiology · 2022
    Review
  10. 5-HT Receptors and the Development of New Antidepressants.International journal of molecular sciences · 2021
    Review
  11. Targeting 5-HTCirculation · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 5 countries.

Arnauld BelmerINSERM UMR-S 839, 75005, Paris, France.ORCID http://orcid.org/0000-0001-6640-5631
Emily QuentinINSERM UMR-S 839, 75005, Paris, France.
Silvina L DiazINSERM UMR-S 839, 75005, Paris, France.
Bruno P GuiardResearch Center on Animal Cognition, Center for Integrative Biology, 31062, Toulouse, France.
Sebastian P FernandezINSERM UMR-S 839, 75005, Paris, France.
Stéphane DolyINSERM UMR-S 839, 75005, Paris, France.
Sophie M BanasINSERM UMR-S 839, 75005, Paris, France.
Pothitos M PitychoutisINSERM UMR-S 839, 75005, Paris, France.
Imane MoutkineINSERM UMR-S 839, 75005, Paris, France.
Aude MuzerelleINSERM UMR-S 839, 75005, Paris, France.
Anna TchenioINSERM UMR-S 839, 75005, Paris, France.
Anne RoumierINSERM UMR-S 839, 75005, Paris, France.
Manuel MameliINSERM UMR-S 839, 75005, Paris, France.
Luc MaroteauxINSERM UMR-S 839, 75005, Paris, France. luc.maroteaux@upmc.fr.ORCID http://orcid.org/0000-0002-9499-8603
Inserm · FRCentre National de la Recherche Scientifique · FRTranslational Research Institute · AUUniversity of Dayton · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT

Indexed as

3,4-Methylenedioxyamphetamine8-Hydroxy-2-(di-n-propylamino)tetralinAction PotentialsAmphetaminesAnimalsBody TemperatureCentral Nervous System SensitizationFemaleFluoxetineIndolesMaleMiceMice, KnockoutMice, TransgenicNeurogenesisPrepulse Inhibition1-(5-(2-thenyloxy)-1H-indol-3-yl)propan-2-amine3,4-Methylenedioxyamphetamine4-iodo-2,5-dimethoxyphenylisopropylamine8-Hydroxy-2-(di-n-propylamino)tetralinAmphetaminesFev protein, mouseFluoxetineIndolesReceptor, Serotonin, 5-HT2BSerotonin 5-HT2 Receptor AgonistsThiophenesTranscription Factors

Identifiers

PMID29453444
PMCPMC5983540
OpenAlexW2794283350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.