Evidence map›Paper›PMID 29453427›Full record

ReviewEuropean journal of clinical nutrition2018

Orthodox religious fasting as a medical nutrition therapy for dyslipidemia: where do we stand and how far can we go?

Theocharis Koufakis, Spyridon N Karras, Pantelis Zebekakis, Kalliopi Kotsa

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Theocharis KoufakisDivision of Endocrinology and Metabolism-Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.ORCID http://orcid.org/0000-0002-5853-1352
Spyridon N KarrasDivision of Endocrinology and Metabolism-Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece. karraspiros@yahoo.gr.
Pantelis ZebekakisDivision of Endocrinology and Metabolism-Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.
Kalliopi KotsaDivision of Endocrinology and Metabolism-Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.ORCID http://orcid.org/0000-0003-2376-740X
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have reported inconclusive results regarding the effects of Orthodox religious fasting (OF) on common cardiovascular risk factors, including arterial hypertension and diabetes. Contrariwise, an optimal effect on dyslipidemia has been demonstrated and significant reductions in total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) concentrations, in Orthodox populations without comorbidities, have been consistently reported. This favorable effect on lipid homeostasis is probably facilitated by a broad lifestyle modification related to OF, extended beyond dietary habits. However, several clinical issues require further clarification by future trials including the efficacy and safety of OF in specific groups of patients with dyslipidemia, mainly those with cardiovascular disease and diabetes, the effects of OF on high-density lipoprotein-cholesterol (HDL-C), the dietary limitations of specific vitamins and minerals during fasting, as well as the optimal duration of this dietary intervention. The present article aims to discuss, whether there is a strong enough theoretical background, to currently support the implementation of OF as a medical nutrition therapy for dyslipidemia in the daily clinical setting, with a discourse on available evidence and future research agenda.

Indexed as

FastingReligionAdultCeremonial BehaviorDyslipidemiasFemaleHumansMaleMiddle Aged

Identifiers

PMID29453427
OpenAlexW2789943458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.