Evidence map›Paper›PMID 29453412›Full record

ArticleMucosal immunology2018

Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma.

Sean R McMaster, Alexander N Wein, Paul R Dunbar, Sarah L Hayward, Emily K Cartwright, Timothy L Denning, Jacob E Kohlmeier

Abstract read
In one paragraph

Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed.

  1. Innate-like Gene Expression of Lung-Resident Memory CD8American journal of respiratory and critical care medicine · 2021
    Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Origins of CD8 tissue resident memory.Frontiers in immunology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. CXCR6 promotes dermal CD8bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Inverted HA-EV immunization elicits stalk-specific influenza immunity and cross-protection in mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  19. Article
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean R McMasterDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Alexander N WeinDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Paul R DunbarDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Sarah L HaywardDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Emily K CartwrightDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Timothy L DenningInstitute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
Jacob E KohlmeierDepartment of Microbiology & Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA. jkohlmeier@emory.edu.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
TRAINING IN IMMUNOLOGY AND MOLECULAR PATHOGENESIST32AI007610 · NIAID · EMORY UNIVERSITY · PI EVAVOLD, BRIAN D · 2000 to 2014
$4.4M
Imprinting of Lung-Resident T Cell MemoryR01HL122559 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2015 to 2019
$1.9M
Regulation of lung TRM maintenance and the decline of pulmonary cellular immunityR01HL138508 · NHLBI · EMORY UNIVERSITY · PI KOHLMEIER, JACOB E · 2017 to 2019
$1.2M
The Role of CXCR6 in Lung Airway Memory T cell Recruitment and MaintenanceF30HL118954 · NHLBI · EMORY UNIVERSITY · PI MCMASTER, SEAN R · 2014 to 2016
$142k
The role of APC's in the establishment of lung tissue resident memory T CellsF31AI124611 · NIAID · EMORY UNIVERSITY · PI DUNBAR, PAUL RICHARD · 2016 to 2018
$132k
NHLBI NIH HHS F30 HL118954NHLBI NIH HHS R01 HL122559NHLBI NIH HHS R01 HL138508NIAID NIH HHS F31 AI124611NIAID NIH HHS HHSN272201400004CNIAID NIH HHS T32 AI007610NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

Resident memory CD8 T (T

Indexed as

AnimalsAntigensAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCD8-Positive T-LymphocytesCells, CulturedHumansImmunologic MemoryInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesIntegrin alpha1beta1Lectins, C-TypeLungLymphocyte ActivationAntigensAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensInfluenza VaccinesIntegrin alpha1beta1Lectins, C-Type

Identifiers

PMID29453412
PMCPMC6030505

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.