Evidence map›Paper›PMID 29453304›Full record

Trial reportBMJ open2018

Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD 'QbTest Utility for Optimising Treatment in ADHD' (QUOTA): a feasibility randomised controlled trial.

Charlotte L Hall, Marilyn James, Sue Brown, Jennifer L Martin, Nikki Brown, Kim Selby, Julie Clarke, Hena Vijayan, Boliang Guo, Kapil Sayal and 2 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03368573 (Optimising Medication Management in Children and Young People With Attention Deficit Hyperactivity Disorder), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03368573 nacompletednot on this map

Optimising Medication Management in Children and Young People With Attention Deficit Hyperactivity Disorder (ADHD) Using an Objective Measure of Attention, Impulsivity and Activity (QbTest): a Feasibility Study

TypeinterventionalSponsorNottinghamshire Healthcare NHS TrustRan2017 to 2018Enrolled43ConditionsADHDArmsQbTest
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD - are we there yet?Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Charlotte L HallInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
Marilyn JamesDivision of Rehabilitation and Ageing, University of Nottingham, Nottingham, UK.
Sue BrownInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
Jennifer L MartinInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
Nikki BrownInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
Kim SelbyDepartment of Community Paediatrics, Medway NHS Foundation Trust, Kent, UK.
Julie ClarkeGrantham and District Hospital, United Lincolnshire Hospitals NHS Trust, Grantham, UK.
Hena VijayanNorth East London NHS Foundation Trust, Acorn Centre, Romford, UK.
Boliang GuoInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
Kapil SayalQueen's Medical Centre, University of Nottingham, Nottingham, UK.
Chris HollisQueen's Medical Centre, University of Nottingham, Nottingham, UK.
Madeleine J GroomInstitute of Mental Health, Division of Psychiatry & Applied Psychology, University of Nottingham, Nottingham, UK.
University of Nottingham · GBInstitute of Mental Health · GBGrantham and District Hospital · GBMedway NHS Foundation Trust · GBNorth East London NHS Foundation Trust · GB

Funding

Department of Health PB-PG-1215-20026
6 · The paper itself

Abstract

introductionAttention-deficit hyperactivity disorder (ADHD) is characterised by symptoms of inattention, hyperactivity and impulsivity. To improve outcomes, the National Institute for Health and Care Excellence ADHD guidelines recommend regular monitoring of symptoms when children commence medication. However, research suggests that routine monitoring rarely happens, and clinicians often rely on subjective information such as reports from parents and teachers to ascertain improvement. These sources can be unreliable and difficult to obtain. The addition of an objective test of attention and activity (QbTest) may improve the objectivity, reliability and speed of clinical decision-making and so reduce the time to identify the optimal medication dose. This study aims to assess the feasibility and acceptability of a QbTest medication management protocol delivered in routine healthcare services for children with ADHD. METHOD AND ANALYSIS: This multisite feasibility randomised controlled trial (RCT) will recruit 60 young people (aged 6-17 years old), diagnosed with ADHD, and starting stimulant medication who are seen by Child and Adolescent Mental Health Services or Community Paediatric services. Participants will be randomised into one of two arms. In the experimental arm (QbTest protocol), the participant will complete a QbTest at baseline (prior to medication initiation), and two follow-up QbTests on medication (2-4 weeks and 8-10 weeks later). In the control arm, participants will receive treatment as usual, with at least two follow-up consultations. Measures of parent-, teacher- and clinician-rated symptoms and global functioning will be completed at each time point. Health economic measures will be completed. Clinicians will record treatment decision-making. Acceptability and feasibility of the protocol will be assessed alongside outcome measure completion rates. Qualitative interviews will be conducted. ETHICS AND DISSEMINATION: The findings will be used to inform the development of a fully powered RCT. The results will be submitted for publication in peer-reviewed journals. The study has ethical approval. TRIAL REGISTRATION NUMBER: NCT03368573; Pre-results.

Indexed as

AttentionImpulsive BehaviorAdolescentAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildFeasibility StudiesFemaleHumansInterdisciplinary CommunicationMaleMedication AdherenceMental Health ServicesNeuropsychological TestsParentsReproducibility of ResultsCentral Nervous System StimulantsADHDcontinous performance test (CPT)medicationQbTesttitrationtreatment

Identifiers

PMID29453304
PMCPMC5829926
OpenAlexW2789291028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.