ArticleJournal of immunology (Baltimore, Md. : 1950)2018
IL-12+IL-18 Cosignaling in Human Macrophages and Lung Epithelial Cells Activates Cathelicidin and Autophagy, Inhibiting Intracellular Mycobacterial Growth.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 74 citations in OpenAlex.
- Ferroptosis in Low-Density Neutrophils of Tuberculosis Patients Suppresses Bactericidal Function.Clinical and experimental pharmacology & physiology · 2026Article
- The Roles of Interleukin-18 in Inflammation and Autoimmune Disease.Clinical reviews in allergy & immunology · 2026Review
- The Role of Vitamin D and Vitamin D Receptor in Sepsis.Current issues in molecular biology · 2025Review
- New insights into pulmonary arterial hypertension: interaction between PANoptosis and perivascular inflammatory responses.Apoptosis : an international journal on programmed cell death · 2025Review
- Molecular Insight into the Role of Vitamin D in Immune-Mediated Inflammatory Diseases.International journal of molecular sciences · 2025Review
- The Role and Potential Application of IL-12 in the Immune Regulation of Tuberculosis.International journal of molecular sciences · 2025Review
- miR-107-enriched exosomes promote ROS/wnt/autophagy, inhibit intracellular mycobacterial growth and attenuate lung infection.Frontiers in immunology · 2025Article
- LncRNA SNHG16 Inhibits IntracellularACS omega · 2024Article
- Analysis of the components of Mycobacterium tuberculosis heat-resistant antigen (Mtb-HAg) and its regulation of γδ T-cell function.Cellular & molecular biology letters · 2024Article
- IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellularFrontiers in immunology · 2024Article
- IL-12 and IL-23 pathway inhibition in inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2023Review
- Inflammation and cognition in severe mental illness: patterns of covariation and subgroups.Molecular psychiatry · 2023Article
- Vitamin D as a Shield against Aging.International journal of molecular sciences · 2023Review
- IL-12p40 is essential but not sufficient for Francisella tularensis LVS clearance in chronically infected mice.PloS one · 2023Article
- Adjunctive Zoledronate + IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosisEmerging microbes & infections · 2022Article
- Vitamin D/vitamin D receptor, autophagy, and infection.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Restricted Activation of the NF-κB Pathway in Individuals with Latent Tuberculosis Infection after HIF-1α Blockade.Biomedicines · 2022Article
- The Transcriptomic Mechanism of a Novel Autolysis Induced by a Recombinant Antibacterial Peptide from Chicken Expressed inMolecules (Basel, Switzerland) · 2022Article
- Article
- Vγ2 x PD-L1, a Bispecific Antibody Targeting Both the Vγ2 TCR and PD-L1, Improves the Anti-Tumor Response of Vγ2Vδ2 T Cell.Frontiers in immunology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Rui YangUnit of Anti-Tuberculosis Immunity, Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0001-7679-9646
Enzhuo YangDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, IL 60612.ORCID 0000-0001-9131-482X
Ling ShenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, IL 60612.
Robert L ModlinDepartment of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0003-4720-031X
Hongbo ShenUnit of Anti-Tuberculosis Immunity, Key Laboratory of Molecular Virology and Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China; hbshen@ips.ac.cn.
Zheng W ChenDepartment of Microbiology and Immunology, Center for Primate Biomedical Research, University of Illinois College of Medicine, Chicago, IL 60612.
University of Illinois Urbana-Champaign · USChinese Academy of Sciences · CNUniversity of California, Los Angeles · US
Funding
Molecular Analysis of the Host Immune Response in LeprosyR01AI022553 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROBERT L MODLIN · 1989 to 2026
$15.7MTCR GAMMA/DELTA LYMPHOCYTES IN HUMAN SKIN LESIONSR01AR040312 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MODLIN, ROBERT L · 1990 to 2025
$10.4MMODEL OF AIDS VIRUS-RELATED PULMONARY TUBERCULOSISR01HL064560 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1999 to 2014
$9.5MSIV/MYCOBACTERIUM COINFECTIONR01RR013601 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1998 to 2008
$4.4MAg-specific gamma delta T cells and immunity to TB/AIDS-related TBR01OD015092 · OD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2013 to 2017
$3.0MAnti-TB sterilizing immunity in immune and HIV+ individualsR01HL129887 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 2015 to 2018
$2.1MNCRR NIH HHS R01 RR013601NHLBI NIH HHS R01 HL064560NHLBI NIH HHS R01 HL129887NIAID NIH HHS R01 AI022553NIAMS NIH HHS R01 AR040312NIH HHS R01 OD015092
Abstract
The ability of
Indexed as
A549 CellsAntimicrobial Cationic PeptidesAutophagyCathelicidinsCell Line, TumorEpithelial CellsHumansImmunity, InnateInterferon-gammaInterleukin-12 Subunit p35Interleukin-18MacrophagesMycobacterium tuberculosisp38 Mitogen-Activated Protein KinasesReceptors, CalcitriolRespiratory MucosaAntimicrobial Cationic PeptidesCathelicidinsIFNG protein, humanIL12A protein, humanInterferon-gammaInterleukin-12 Subunit p35Interleukin-18p38 Mitogen-Activated Protein KinasesReceptors, CalcitriolSTAT4 protein, humanSTAT4 Transcription Factor
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.