ArticleProceedings of the National Academy of Sciences of the United States of America2018
Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- From Microbial Dynamics to Functionality in the Rhizosphere: A Systematic Review of the Opportunities With Synthetic Microbial Communities.Frontiers in plant science · 2021Pooled it
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- Plant and aphid genotypes modulate legume rhizobium-induced defense against aphids.BMC plant biology · 2026Article
- Host-specific fluorescence dynamics in legume-rhizobium symbiosis during nodulation.Applied and environmental microbiology · 2026Article
- Genomic signatures inmSystems · 2026Article
- Mutations in legume genes that influence symbiosis create a complex selective landscape for rhizobial symbionts.The ISME journal · 2026Article
- Polyhydroxyalkanoate synthesis by Sinorhizobium meliloti drives a host-specific collapse in symbiosis with Medicago sativa.Research square · 2025Article
- "Select and Resequence" Methods Enable a Genome-Wide Association Study of the Dimorphic Human Fungal Pathogen Coccidioides posadasii.Genome biology and evolution · 2025Article
- Virulence is not directly related to strain successmSystems · 2025Article
- Increased diversity of beneficial rhizobia enhances faba bean growth.Nature communications · 2024Article
- Rhizobial variation, more than plant variation, mediates plant symbiotic and fitness responses to herbicide stress.Ecology · 2024Article
- Genotypic variation in resource exchange, use, and production traits in the legume-rhizobia mutualism.Ecology and evolution · 2024Article
- Embracing complexity in plant-microbiome systems.Environmental microbiology reports · 2024Review
- The impacts of host association and perturbation on symbiont fitness.Symbiosis (Philadelphia, Pa.) · 2024Article
- Rhizosphere frame system enables nondestructive live-imaging of legume-rhizobium interactions in the soil.Journal of plant research · 2023Article
- Colonization-persistence trade-offs in natural bacterial communities.Proceedings. Biological sciences · 2023Article
- A Selective Bottleneck During Host Entry Drives the Evolution of New Legume Symbionts.Molecular biology and evolution · 2023Article
- Evaluation of qPCR to Detect Shifts in Population Composition of the Rhizobial SymbiontBiology · 2023Article
- Deciphering factors driving soil microbial life-history strategies in restored grasslands.iMeta · 2023Article
- Hosts winnow symbionts with multiple layers of absolute and conditional discrimination mechanisms.Proceedings. Biological sciences · 2023Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assays to accurately estimate relative fitness of bacteria growing in multistrain communities can advance our understanding of how selection shapes diversity within a lineage. Here, we present a variant of the "evolve and resequence" approach both to estimate relative fitness and to identify genetic variants responsible for fitness variation of symbiotic bacteria in free-living and host environments. We demonstrate the utility of this approach by characterizing selection by two plant hosts and in two free-living environments (sterilized soil and liquid media) acting on synthetic communities of the facultatively symbiotic bacterium
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.