ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018
Hippocampal Ripple Oscillations and Inhibition-First Network Models: Frequency Dynamics and Response to GABA Modulators.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 50 citations in OpenAlex.
- The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Trial
- Conditions for replay of neuronal assemblies.PLoS computational biology · 2026Article
- Study on the Mechanism of Mongolian Medical Warm Acupuncture in Regulating Biological Clock Genes and Improving Sleep in Insomniac Rats.Current medicinal chemistry · 2026Article
- Cholinergic modulation of neural networks supports sequential and complementary roles for NREM and REM states in memory consolidation.PLoS computational biology · 2025Article
- Regulation of sharp wave-ripples by cholecystokinin-expressing interneurons and parvalbumin-expressing basket cells in the hippocampal CA3 region.Frontiers in computational neuroscience · 2025Article
- GABAergic integration of transient and persistent neurons in the developing mouse somatosensory cortex.Frontiers in cellular neuroscience · 2025Article
- Differences in the consolidation by spontaneous and evoked ripples in the presence of active dendrites.PLoS computational biology · 2024Article
- Intra-ripple frequency accommodation in an inhibitory network model for hippocampal ripple oscillations.PLoS computational biology · 2024Article
- A developmental increase of inhibition promotes the emergence of hippocampal ripples.Nature communications · 2024Article
- Article
- High-frequency oscillations and sequence generation in two-population models of hippocampal region CA1.PLoS computational biology · 2022Article
- Neuregulin 1 and ErbB4 Kinase Actively Regulate Sharp Wave Ripples in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Article
- A computational study of suppression of sharp wave ripple complexes by controlling calcium and gap junctions in pyramidal cells.Bioengineered · 2021Article
- Mapping input noise to escape noise in integrate-and-fire neurons: a level-crossing approach.Biological cybernetics · 2021Article
- Regulating synchronous oscillations of cerebellar granule cells by different types of inhibition.PLoS computational biology · 2021Article
- Subiculum as a generator of sharp wave-ripples in the rodent hippocampus.Cell reports · 2021Article
- Gating of hippocampal rhythms and memory by synaptic plasticity in inhibitory interneurons.Neuron · 2021Article
- Generation of Sharp Wave-Ripple Events by Disinhibition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Modelling unitary fields and the single-neuron contribution to local field potentials in the hippocampus.The Journal of physiology · 2020Article
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4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hippocampal ripples are involved in memory consolidation, but the mechanisms underlying their generation remain unclear. Models relying on interneuron networks in the CA1 region disagree on the predominant source of excitation to interneurons: either "direct," via the Schaffer collaterals that provide feedforward input from CA3 to CA1, or "indirect," via the local pyramidal cells in CA1, which are embedded in a recurrent excitatory-inhibitory network. Here, we used physiologically constrained computational models of basket-cell networks to investigate how they respond to different conditions of transient, noisy excitation. We found that direct excitation of interneurons could evoke ripples (140-220 Hz) that exhibited intraripple frequency accommodation and were frequency-insensitive to GABA modulators, as previously shown in
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.