Evidence map›Paper›PMID 29452623›Full record

ReviewSeminars in nuclear medicine2018

Currently Available Radiopharmaceuticals for Imaging Infection and the Holy Grail.

Ebru Salmanoglu, Sung Kim, Mathew L Thakur

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in nuclear medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Understanding bacterial biofilms: From definition to treatment strategies.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
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  10. Review
  11. Review
  12. Review
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  14. Intrathecal Antibacterial and Antifungal Therapies.Clinical microbiology reviews · 2020
    Review
  15. Article
  16. Article
  17. Diagnostic Performance of PET or PET/CT UsingDiagnostics (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ebru SalmanogluDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA 19107; Department of Nuclear Medicine, Kahramanmaras Sutcu Imam University Faculty of Medicine, Avsar Kampus, Kahramanmaras 46040, Turkey.
Sung KimDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA 19107.
Mathew L ThakurDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA 19107; Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107. Electronic address: Madhukar.Thakur@jefferson.edu.
Thomas Jefferson University · US

Funding

VPAC1 Recpetor-Targeted PET Imaging of Prostate CancerR01CA157372 · NCI · THOMAS JEFFERSON UNIVERSITY · PI THAKUR, MATHEW LAXMAN · 2012 to 2017
$2.6M
NCI NIH HHS R01 CA157372
6 · The paper itself

Abstract

Infection is ubiquitous. However, its management is challenging for both the patients and the health-care providers. Scintigraphic imaging of infection dates back nearly half a century. The advances in our understanding of the pathophysiology of disease at cellular and molecular levels have paved the way to the development of a large number of radiopharmaceuticals for scintigraphic imaging of infection. These include radiolabeling of blood elements such as serum proteins, white blood cells (WBCs), and cytokines, to name a few. Infectious foci have also been imaged using a radiolabeled sugar molecule by taking advantage of increased metabolic activity in the infectious lesions. Literature over the years has well documented that none of the radiopharmaceuticals and associated procedures that facilitate imaging infection are flawless and acceptable without a compromise. As a result, only a few compounds such as

Indexed as

RadiopharmaceuticalsHumansInfectionsLeukocytesMolecular ImagingRadiopharmaceuticals

Identifiers

PMID29452623
PMCPMC6487501
OpenAlexW2786975892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.