ArticleJournal of diabetes investigation2018
Serum adiponectin and insulin secretion: A direct or inverse association?
Article in Journal of diabetes investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
17 citing papers in PubMed.
- Improved Insulin Secretion Response and Beta-cell Function Correlated with Increased Prolactin Levels After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients with Acanthosis Nigricans.Obesity surgery · 2023Article
- Serum 25-hydroxyvitamin DJournal of epidemiology · 2023Article
- Metabolic Profiling of Pregnant Women with Obesity: An Exploratory Study in Women at Greater Risk of Gestational Diabetes.Metabolites · 2022Article
- Adipose Tissue Secretion Pattern Influences β-Cell Wellness in the Transition from Obesity to Type 2 Diabetes.International journal of molecular sciences · 2022Review
- Article
- Inverse correlation between serum high-molecular-weight adiponectin and proinsulin level in a Japanese population: The Dynamics of Lifestyle and Neighborhood Community on Health Study.Journal of diabetes investigation · 2021Article
- Characteristics associated with elevated 1-h plasma glucose levels during a 75-g oral glucose tolerance test in non-obese Japanese men.Journal of diabetes investigation · 2020Observational
- Insulin and Proinsulin Dynamics Progressively Deteriorate From Within the Normal Range Toward Impaired Glucose Tolerance.Journal of the Endocrine Society · 2020Article
- Correlation between serum proinsulin levels and fatty liver: The Dynamics of Lifestyle and Neighborhood Community on Health Study.Journal of diabetes investigation · 2020Article
- Clinical evidence regarding factors linking metabolic abnormal obesity to pancreatic β-cell dysfunction.Journal of diabetes investigation · 2020Article
- Prospective Study of Long-Term Interrelationships Among Adiposity-Associated Biomarkers in Women.Obesity (Silver Spring, Md.) · 2020Article
- AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells.Journal of oncology · 2020Article
- Proinsulin is sensitive to reflect glucose intolerance.Journal of diabetes investigation · 2020Article
- Protein Kinase CK2-A Putative Target for the Therapy of Diabetes Mellitus?International journal of molecular sciences · 2019Review
- The Association of Adiponectin and Visceral Fat with Insulin Resistance and β-Cell Dysfunction.Journal of Korean medical science · 2019Article
- Serum adiponectin and insulin secretion: A direct or inverse association?Journal of diabetes investigation · 2018Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
We investigated the association between serum high molecular weight (HMW) adiponectin and insulin secretion in a population-based study, with or without adjustment for insulin sensitivity. A total of 488 participants (263 women) were included in the present study. Insulin secretion was estimated using the homeostasis model assessment of β-cell function ± adjustment for insulin resistance using the disposition index. Multivariate analysis showed that HMW adiponectin was significantly and inversely associated with homeostasis model assessment of β-cell function (partial regression coefficient -0.19, 95% confidence interval -0.28, -0.10, P < 0.0001). However, HMW adiponectin was significantly and positively associated with disposition index (partial regression coefficient 0.15, 95% confidence interval 0.06, 0.24, P = 0.0016). The present study showed that a positive association between HMW adiponectin levels and insulin secretion evaluated using an index incorporating adjustment for insulin resistance was identified, and vice versa using an index that did not adjust for insulin resistance.
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Registered trials
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