ArticleMolecular ecology2018
Transitions in sex determination and sex chromosomes across vertebrate species.
Article in Molecular ecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
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Who cites it
83 citing papers in PubMed, 170 citations in OpenAlex.
- Unique sex chromosome translocations and evolutionary strata in two Sylvioidea songbird families.BMC genomics · 2026Article
- Chromosome-specific drift under stabilizing selection generates polygenic barriers to sex chromosome turnover.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Different sex determination systems in two closely related Eurasian minnow (Phoxinus) species.Heredity · 2026Article
- Genome-Wide Characterization of Sex-Linked Regions in the Sangzhi Horned Toad (Boulenophrys sangzhiensis) Reveals Complex Sex Determination Mechanisms.Molecular ecology resources · 2026Article
- Amhy/Amhr2y-mediated sex determination in two distantly related teleosts relies on the conserved Alk3-Smad5 axis.Molecular biology and evolution · 2026Article
- Evolutionary dynamics of sex determination in Branchiostoma belcheri driven by repeated transposition of a single novel gene.Nature communications · 2026Article
- A novel sex-associated genomic region in Catostomus fish species.The Journal of heredity · 2025Article
- The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.Journal of evolutionary biology · 2025Article
- Rapid Sex Chromosome Turnover in African Clawed Frogs (Xenopus) and the Origins of New Sex Chromosomes.Molecular biology and evolution · 2024Article
- Neo-Sex Chromosome Evolution in Treehoppers Despite Long-Term X Chromosome Conservation.Genome biology and evolution · 2024Article
- The male and female genomes of golden pompano (Trachinotus ovatus) provide insights into the sex chromosome evolution and rapid growth.Journal of advanced research · 2024Article
- Protein expression patterns and metal metabolites in a protogynous hermaphrodite fish, the ricefield eel (Monopterus albus).BMC genomics · 2024Article
- Lack of Dosage Balance and Incomplete Dosage Compensation in the ZZ/ZW Gila Monster (Heloderma suspectum) Revealed by De Novo Genome Assembly.Genome biology and evolution · 2024Article
- Multiple Transitions between Y Chromosome and Autosome in Tago's Brown Frog Species Complex.Genes · 2024Article
- A high-quality reference genome for the common creek chub, Semotilus atromaculatus.G3 (Bethesda, Md.) · 2024Article
- Turnover of sex chromosomes in the Lake Tanganyika cichlid tribe Tropheini (Teleostei: Cichlidae).Scientific reports · 2024Article
- Assembly of the poorly differentiated Verasper variegatus W chromosome by different sequencing technologies.Scientific data · 2023Article
- Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotype organization.Genome research · 2023Article
- Context-dependent thermolability of sex determination in a lacertid lizard with heteromorphic sex chromosomes.Biology open · 2023Article
- Incomplete dosage balance and dosage compensation in the ZZ/ZW Gila monster (bioRxiv : the preprint server for biology · 2023Article
23 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
Abstract
Despite the prevalence of sexual reproduction across eukaryotes, there is a remarkable diversity of sex-determination mechanisms. The underlying causes of this diversity remain unclear, and it is unknown whether there are convergent trends in the directionality of turnover in sex-determination mechanisms. We used the recently assembled Tree of Sex database to assess patterns in the evolution of sex-determination systems in the remarkably diverse vertebrate clades of teleost fish, squamate reptiles and amphibians. Contrary to theoretical predictions, we find no evidence that the evolution of separate sexes is irreversible, as transitions from separate sexes to hermaphroditism occur at higher rates than the reverse in fish. We also find that transitions from environmental sex determination to genetic sex determination occur at higher rates than the reverse in both squamates and fish, suggesting that genetic sex determination is more stable. However, our data are not consistent with the hypothesis that heteromorphic sex chromosomes are an "evolutionary trap." Rather, we find similar transition rates between homomorphic and heteromorphic sex chromosomes in both fish and amphibians, and to environmental sex determination from heteromorphic vs. homomorphic sex chromosome systems in fish. Finally, we find that transitions between male and female heterogamety occur at similar rates in amphibians and squamates, while transitions to male heterogamety occur at higher rates in fish. Together, these results provide the most comprehensive view to date of the evolution of vertebrate sex determination in a phylogenetic context, providing new insight into long-standing questions about the evolution of sexual reproduction.
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