Evidence map›Paper›PMID 29451621›Full record

SynthesisClinics (Sao Paulo, Brazil)2018

A comparison of the efficiency of 22G versus 25G needles in EUS-FNA for solid pancreatic mass assessment: A systematic review and meta-analysis.

Hugo Gonçalo Guedes, Diogo Turiani Hourneaux de Moura, Ralph Braga Duarte, Martin Andres Coronel Cordero, Marcos Eduardo Lera Dos Santos, Spencer Cheng, Sergio Eiji Matuguma, Dalton Marques Chaves, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura

Open access · goldAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinics (Sao Paulo, Brazil), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Endo-hepatology: Bridging the gap between lumen and liver.World journal of gastroenterology · 2025
    Review
  2. Evolution of transbronchial needle aspiration needles: Over the last half century.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  3. Contrast-enhanced guided endoscopic ultrasound procedures.World journal of gastroenterology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Endoscopic ultrasound fine needle aspirationWorld journal of clinical cases · 2021
    Article
  9. Endoscopic ultrasound fine needle aspirationWorld journal of gastroenterology · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hugo Gonçalo GuedesDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Diogo Turiani Hourneaux de MouraDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Ralph Braga DuarteDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Martin Andres Coronel CorderoDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Marcos Eduardo Lera Dos SantosDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Spencer ChengDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Sergio Eiji MatugumaDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Dalton Marques ChavesDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Wanderley Marques BernardoDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Eduardo Guimarães Hourneaux de MouraDivisao de Endoscopia Gastrointestinal, Faculdade de Medicina FMUSP, Universidade de São Paulo, Sao Paulo, SP, BR.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim in this study was to compare the efficiency of 25G versus 22G needles in diagnosing solid pancreatic lesions by EUS-FNA. We performed a systematic review and meta-analysis. Studies were identified in five databases using an extensive search strategy. Only randomized trials comparing 22G and 25G needles were included. The results were analyzed by fixed and random effects. A total of 504 studies were found in the search, among which 4 randomized studies were selected for inclusion in the analysis. A total of 462 patients were evaluated (233: 25G needle/229: 22G needle). The diagnostic sensitivity was 93% for the 25G needle and 91% for the 22G needle. The specificity of the 25G needle was 87%, and that of the 22G needle was 83%. The positive likelihood ratio was 4.57 for the 25G needle and 4.26 for the 22G needle. The area under the sROC curve for the 25G needle was 0.9705, and it was 0.9795 for the 22G needle, with no statistically significant difference between them (p=0.497). Based on randomized studies, this meta-analysis did not demonstrate a significant difference between the 22G and 25G needles used during EUS-FNA in the diagnosis of solid pancreatic lesions.

Indexed as

Data AccuracyEfficiencyEndoscopic Ultrasound-Guided Fine Needle AspirationHumansLikelihood FunctionsNeedlesPancreasPancreatic NeoplasmsRandomized Controlled Trials as TopicSensitivity and Specificity

Identifiers

PMID29451621
PMCPMC5773825
OpenAlexW2787681385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.