ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Psychoactive substance abuse and dependence and its association with anxiety disorders: a population-based study of young adults in Brazil.
Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Substance use and generalized anxiety disorder in university students: evidence from the university of Douala, Cameroon.BMC psychiatry · 2025Article
- The impact of PTSD on risk of cardiometabolic diseases: a national patient cohort study in Norway.BMC psychiatry · 2023Article
- The Role of Anxiety in Smoking Onset, Severity, and Cessation-Related Outcomes: a Review of Recent Literature.Current psychiatry reports · 2020Review
- Correlation of Alcohol Use Disorders with Common Mental Disorders and Its Association with Socio-demographic Characteristics Among Community in Ethiopia: A Cross-sectional Study.Risk management and healthcare policy · 2020Article
- Psychiatric comorbidities in alcohol use disorder.The lancet. Psychiatry · 2019Article
- Direct healthcare costs and their relationships with age at start of drug use and current pattern of use: a cross-sectional study.Sao Paulo medical journal = Revista paulista de medicinaArticle
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
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Abstract
objectiveTo evaluate the association between abuse of and dependence on different psychoactive substances and the presence of anxiety disorders in a sample of young adults from a city in southern Brazil.
methodsBetween 2007 and 2009, we carried out a cross-sectional, population-based study of individuals aged 18-24 years who lived in Pelotas, a city in southern Brazil. We evaluated anxiety disorders using the Mini International Neuropsychiatric Interview 5.0 (MINI), and use of psychoactive substances with the Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST 2.0/0MS). We used Fisher's exact test for univariate analysis, and Poisson regression models with robust variance for multivariable analysis.
resultsThe sample consisted of 1,560 young adults. The overall prevalence of abuse/dependence was 26.9% for alcohol, 24.9% for tobacco, and 7.3% for illicit substances. Individuals with agoraphobia had a 32% higher prevalence of tobacco abuse/dependence (prevalence ratio [PR] = 1.32 [95%CI 1.01-1.74]). Individuals with posttraumatic stress disorder (PTSD) or generalized anxiety disorder (GAD) had a 2.41-fold (95%CI 1.22-4.77) and 1.76-fold (95%CI 1.00-3.11) higher prevalence of illicit substance abuse/dependence, respectively.
conclusionIn this population-based sample, we found associations between GAD, PTSD, and increased prevalence of illicit substance abuse/dependence. In addition, individuals with agoraphobia seem to have increased tobacco abuse/dependence.
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