Evidence map›Paper›PMID 29451444›Full record

ArticleJournal of feline medicine and surgery2018

Survival and prognostic factors in cats with restrictive cardiomyopathy: a review of 90 cases.

Chiara Locatelli, Danitza Pradelli, Giulia Campo, Ilaria Spalla, Alice Savarese, Paola G Brambilla, Claudio Bussadori

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Dosage of Pimobendan in Domestic Cats.Veterinary medicine international · 2026
    Review
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  6. Journal of feline medicine and surgery · 2023
    Article
  7. Article
  8. The Feline Cardiomyopathies: 1. General concepts.Journal of feline medicine and surgery · 2021
    Article
  9. The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021
    Article
  10. The Feline Cardiomyopathies: 3. Cardiomyopathies other than HCM.Journal of feline medicine and surgery · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chiara Locatelli1 Department of Veterinary Medicine, University of Milan, Milan, Italy.
Danitza Pradelli2 Gran Sasso Veterinary Clinic, Milan, Italy.
Giulia Campo1 Department of Veterinary Medicine, University of Milan, Milan, Italy.
Ilaria Spalla3 Royal Veterinary College, Hatfield, UK.
Alice Savarese1 Department of Veterinary Medicine, University of Milan, Milan, Italy.
Paola G Brambilla1 Department of Veterinary Medicine, University of Milan, Milan, Italy.
Claudio Bussadori2 Gran Sasso Veterinary Clinic, Milan, Italy.
University of Milan · ITRoyal Veterinary College · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLarge studies focusing on restrictive cardiomyopathy (RCM) in the cat are scarce. The aims of this retrospective study were to describe epidemiological characteristics and to analyse prognostic factors affecting survival in cats with RCM.

methodsThe clinical archives of the Gran Sasso Veterinary Clinic (Milan, Italy) and of the cardiology unit of the Department of Veterinary Medicine (University of Milan, Italy) from 1997-2015 were reviewed for all cats diagnosed with RCM based on an echocardiographic examination (left atrial/biatrial enlargement, normal left ventricle wall thickness, normal or mildly decreased systolic function and restrictive left ventricle filling pattern with pulsed Doppler echocardiography).

resultsThe study population comprised 90 cats (53 male, 37 female) with an echocardiographic diagnosis of RCM. Most were domestic shorthairs (n = 60) with a mean ± SD age of 10.0 ± 4.3 years and a median weight of 3.8 kg (interquartile range 3.2-5 kg). Most cats were symptomatic (n = 87). The most common clinical sign was respiratory distress (n = 75). Follow-up was available for 60 cats and the median survival time (MST) was 69 days (95% confidence interval [CI] 0-175 days). Cardiac-related death occurred in 50 cats. In the multivariate Cox analysis only respiratory distress showed a statistically significant effect on survival. The cats without respiratory distress showed an MST of 466 days (95% CI 0-1208); cats with respiratory distress showing an MST of 64 days (95% CI 8-120; P = 0.011). CONCLUSIONS AND RELEVANCE: RCM can be considered an end-stage condition associated with a poor prognosis, with few cats not showing clinical signs and surviving >1 year. Most cats died of cardiac disease within a very short time.

Indexed as

AnimalsCardiomyopathiesCardiomyopathy, RestrictiveCat DiseasesCatsEchocardiographyFemaleItalyMalePrognosisRecordsRetrospective StudiesRisk FactorsSurvival Analysis

Identifiers

PMID29451444
PMCPMC11104218
OpenAlexW2792536986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.