Evidence map›Paper›PMID 29451323›Full record

ArticleAnnals of neurology2018

[

Keith A Josephs, Peter R Martin, Hugo Botha, Christopher G Schwarz, Joseph R Duffy, Heather M Clark, Mary M Machulda, Jonathan Graff-Radford, Stephen D Weigand, Matthew L Senjem and 9 more

Open access · greenAbstract read
In one paragraph

Article in Annals of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 86 citations in OpenAlex.

  1. Review
  2. Identifying neuropathologic disease in primary progressive aphasia using narrative speech.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Microscopy assessment of a fluorescence [Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Clinicoradiological and neuropathological evaluation of primary progressive aphasia.Journal of neurology, neurosurgery, and psychiatry · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Frontotemporal Dementia, Where Do We Stand? A Narrative Review.International journal of molecular sciences · 2023
    Review
  13. Feasibility ofEuropean radiology · 2023
    Article
  14. [European journal of nuclear medicine and molecular imaging · 2023
    Article
  15. The Adult Neurogenesis Theory of Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2023
    Article
  16. Article
  17. Article
  18. The tauopathies: Neuroimaging characteristics and emerging experimental therapies.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Keith A JosephsDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Peter R MartinDepartment of Health Science Research (Biostatistics), Mayo Clinic, Rochester, MN.
Hugo BothaDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Christopher G SchwarzDepartment of Neuroradiology, Mayo Clinic, Rochester, MN.ORCID 0000-0002-1466-8357
Joseph R DuffyDepartment of Speech Pathology (Neurology), Mayo Clinic, Rochester, MN.
Heather M ClarkDepartment of Speech Pathology (Neurology), Mayo Clinic, Rochester, MN.
Mary M MachuldaDepartment of Neuropsychology (Psychiatry), Mayo Clinic, Rochester, MN.
Jonathan Graff-RadfordDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Stephen D WeigandDepartment of Health Science Research (Biostatistics), Mayo Clinic, Rochester, MN.
Matthew L SenjemDepartment of Information Technology, Mayo Clinic, Rochester, MN.
Rene L UtianskiDepartment of Speech Pathology (Neurology), Mayo Clinic, Rochester, MN.
Daniel A DrubachDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Bradley F BoeveDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
David T JonesDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
David S KnopmanDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Ronald C PetersenDepartment of Behavioral Neurology, Mayo Clinic, Rochester, MN.
Clifford R JackDepartment of Neuroradiology, Mayo Clinic, Rochester, MN.
Val J LoweDepartment of Nuclear Medicine (Radiology), Mayo Clinic, Rochester, MN.
Jennifer L WhitwellDepartment of Neuroradiology, Mayo Clinic, Rochester, MN.
Mayo Clinic · USMayo Clinic in Arizona · US

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
Longitudinal multi-modality imaging in progressive apraxia of speech (Diversity Supplement)R01DC012519 · NIDCD · MAYO CLINIC ROCHESTER · PI Jennifer Louise Whitwell · 2013 to 2026
$7.2M
Molecular and structural imaging in atypical Alzheimer's disease: a longitudinal studyR01AG050603 · NIA · MAYO CLINIC ROCHESTER · PI WHITWELL, JENNIFER LOUISE · 2016 to 2025
$5.9M
Assessment of hyperphosphorylated tau PET binding in primary progressive aphasiaR21NS094684 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2016 to 2017
$417k
NIA NIH HHS R01 AG050603NIA NIH HHS U01 AG006786NIDCD NIH HHS R01 DC012519NINDS NIH HHS R21 NS094684
6 · The paper itself

Abstract

objectivesTo assess [

methodsWe performed statistical parametric mapping of [

resultsLogopenic-PPA showed striking uptake throughout neocortex, particularly temporoparietal, compared to controls, semantic-PPA, and agrammatic-PPA. Semantic-PPA and agrammatic-PPA showed milder patterns of focal [

interpretation[

Indexed as

AgedAphasiaAphasia, Primary ProgressiveBrainCarbolinesCognitionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsPositron-Emission TomographyWhite Matter7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolines

Identifiers

PMID29451323
PMCPMC5896771
OpenAlexW2791509387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.