Evidence map›Paper›PMID 29450867›Full record

ArticleJournal of endocrinological investigation2018

20S proteasome in the blood plasma of boys with cryptorchidism.

D Toliczenko-Bernatowicz, E Matuszczak, M Tylicka, A Sankiewicz, M Komarowska, E Gorodkiewicz, W Debek, A Hermanowicz

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Article in Journal of endocrinological investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

D Toliczenko-BernatowiczPaediatric Surgery Department, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
E MatuszczakPaediatric Surgery Department, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland. ewamat@tlen.pl.
M TylickaBiophysics Department, Medical University of Bialystok, Bialystok, Poland.
A SankiewiczElectrochemistry Department, University of Bialystok, Bialystok, Poland.
M KomarowskaPaediatric Surgery Department, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
E GorodkiewiczElectrochemistry Department, University of Bialystok, Bialystok, Poland.
W DebekPaediatric Surgery Department, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
A HermanowiczPaediatric Surgery Department, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
Medical University of Białystok · PLUniversity of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the concentration of 20S proteasome in the blood plasma of boys with cryptorchidism.

methodsPatients-50 boys aged 1-4 years (median = 2.4 years) with unilateral cryptorchidism. The control group-50 healthy, age-matched boys (aged 1-4 years, median = 2.1 years), admitted for planned herniotomy. In our study, we used a novel technique Surface PLASMON RESONANCE Imaging.

resultsThe median concentration of 20S proteasome in the blood plasma of boys with cryptorchidism was 2.5-fold higher than in boys with inguinal hernia. We noticed statistically significant difference between 20S proteasome levels in boys with cryptorchidism up to 2 years old and above 2 years old.

conclusionsWe believe that the 20S proteasome concentrations in the blood plasma of boys with cryptorchidism reflect the heat-induced apoptosis of germ cells.

Indexed as

ApoptosisBiomarkersChild, PreschoolCryptorchidismHumansInfantMaleProteasome Endopeptidase ComplexBiomarkersProteasome Endopeptidase ComplexBoysCryptorchidismProteasomeSPR imaging

Identifiers

PMID29450867
OpenAlexW2789771385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.