ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018
Hysterectomy and perceived physical function in middle-aged Australian women: a 20-year population-based prospective cohort study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 28 citations in OpenAlex.
- Uterus-preserving surgical management of placenta accreta spectrum disorder: a large retrospective study.BMC pregnancy and childbirth · 2023Trial
- Habitual physical activity and sedentary behavior among women with and without premenopausal bilateral oophorectomy: an exploratory study.Menopause (New York, N.Y.) · 2025Article
- Association Between Hysterectomy and Accelerated Aging: Protective Effect of Dietary Fiber and Mediating Role of Creatinine.International journal of women's health · 2025Article
- Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany.BMC public health · 2023Article
- Prevalence of Hysterectomy by Self-Reported Disability Among Canadian Women: Findings from a National Cross-Sectional Survey.Women's health reports (New Rochelle, N.Y.) · 2021Article
- Trends in Hysterectomy Incidence Rates During 2000-2015 in Denmark: Shifting from Abdominal to Minimally Invasive Surgical Procedures.Clinical epidemiology · 2021Article
- What is the impact of PPAR-γ agonist-rosiglitazone on ovarian reserve after hysterectomy? An experimental studyTurkish journal of medical sciences · 2020Article
- Loss of Ovarian Hormones and Accelerated Somatic and Mental Aging.Physiology (Bethesda, Md.) · 2018Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeHysterectomy is one of the most common gynaecological procedures worldwide. Changes in endocrine function may impact age-associated decline in physical function and these changes may be accelerated by hysterectomy. The aim of this study was to investigate associations between hysterectomy status and self-reported physical function limitations.
methodsOur study sample (n = 8624) came from the mid-cohort (born 1945-1950) of the Australian Longitudinal Study on Women's Health (ALSWH). Self-report of physical function was measured by the Physical Functioning (PF) subscale of the Medical Outcomes Study Short Form Health Survey (SF-36) over seven surveys (1998-2016), categorised into substantial, moderate and minimal PF-limitations. The associations between hysterectomy status and de novo substantial or moderate PF-limitations versus minimal PF-limitations were investigated using log-multinomial regression.
resultsBy Survey 8 (2016), 20% of the study sample had a hysterectomy with ovarian conservation (hysterectomy only) and 9% had a hysterectomy and both ovaries removed (hysterectomy-bilateral oophorectomy). Women with a hysterectomy only had a small increase in risk of substantial PF-limitations (versus minimal PF-limitations) compared to women with no hysterectomy (relative risk [RR]: 1.13; 95% confidence interval [95% CI] 1.00-1.27); the point estimate was stronger for women with a hysterectomy-bilateral oophorectomy (RR: 1.26; 95% CI 1.09-1.46). In a supplementary analysis, the increased risk of substantial PF-limitations was seen only in women who had surgery before the age of 45 years.
conclusionsCompared to women with no hysterectomy, women with hysterectomy-bilateral oophorectomy were at increased risk of substantial PF-limitations versus minimal PF-limitations over 18 years of follow-up.
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