Evidence map›Paper›PMID 29450820›Full record

ArticleJournal of abnormal child psychology2018

Overlapping and Distinct Cognitive Impairments in Attention-Deficit/Hyperactivity and Autism Spectrum Disorder without Intellectual Disability.

Sarah L Karalunas, Elizabeth Hawkey, Hanna Gustafsson, Meghan Miller, Marybeth Langhorst, Michaela Cordova, Damien Fair, Joel T Nigg

Abstract read
In one paragraph

Article in Journal of abnormal child psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Review
  8. Article
  9. Article
  10. Patterns of Early Development in Children with ADHD.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Neurophysiology of Perceptual Decision-Making and Its Alterations in Attention-Deficit Hyperactivity Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  18. Slow but Steady: Similarities and Differences in Executive Functioning Between Autistic and Non-Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah L KaralunasDepartment of Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., UHN80R1, Portland, OR, 97239, USA. karaluna@ohsu.edu.
Elizabeth HawkeyDepartment of Behavioral Neuroscience, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L470, Portland, OR, 97239, USA.
Hanna GustafssonDepartment of Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., UHN80R1, Portland, OR, 97239, USA.
Meghan MillerDepartment of Psychiatry & Behavioral Sciences and MIND Institute, University of California, Davis, 2825 50th St, Sacramento, CA, 95817, USA.
Marybeth LanghorstDepartment of Behavioral Neuroscience, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L470, Portland, OR, 97239, USA.
Michaela CordovaDepartment of Behavioral Neuroscience, Oregon Health & Science University, 3181 SW Sam Jackson Park Road L470, Portland, OR, 97239, USA.
Damien FairDepartment of Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., UHN80R1, Portland, OR, 97239, USA.
Joel T NiggDepartment of Psychiatry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd., UHN80R1, Portland, OR, 97239, USA.

Funding

Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDR01MH096773 · NIMH · UNIVERSITY OF MINNESOTA · PI DOSENBACH, NICO, FAIR, DAMIEN A · 2012 to 2024
$9.4M
ADHD heterogeneity, mechanisms, and risk profileR37MH059105 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 2014 to 2023
$7.0M
Brain trajectories in ADHDR01MH115357 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, NIGG, JOEL T · 2017 to 2021
$3.8M
Longitudinal Imaging Study of ADHD Brain DevelopmentR01MH086654 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI NIGG, JOEL T · 2010 to 2014
$2.9M
Neurophysiological mechanisms of cognitive and emotional control in ADHDK23MH108656 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI KARALUNAS, SARAH LYN · 2016 to 2019
$742k
Functional Circuits as an Endophenotype for ADHD in ChildrenR00MH091238 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A · 2011 to 2013
$723k
NIMH NIH HHS K23 MH108656NIMH NIH HHS R00 MH091238NIMH NIH HHS R01 MH086654NIMH NIH HHS R01 MH096773NIMH NIH HHS R01 MH115357NIMH NIH HHS R37 MH059105
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are commonly comorbid, share genetic liability, and often exhibit overlapping cognitive impairments. Clarification of shared and distinct cognitive effects while considering comorbid symptoms across disorders has been lacking. In the current study, children ages 7-15 years assigned to three diagnostic groups:ADHD (n = 509), ASD (n = 97), and controls (n = 301) completed measures spanning the cognitive domains of attention/arousal, working memory, set-shifting, inhibition, and response variability. Specific processes contributing to response variability were examined using a drift diffusion model, which separately quantified drift rate (i.e., efficiency of information processing), boundary separation (i.e., speed-accuracy trade-offs), and non-decision time. Children with ADHD and ASD were impaired on attention/arousal, processing speed, working memory, and response inhibition, but did not differ from controls on measures of delayed reward discounting, set-shifting, or interference control. Overall, impairments in the ASD group were not attributable to ADHD symptoms using either continuous symptom measures or latent categorical grouping approaches. Similarly, impairments in the ADHD group were not attributable to ASD symptoms. When specific RT parameters were considered, children with ADHD and ASD shared impairments in drift rate. However, children with ASD were uniquely characterized by a wider boundary separation. Findings suggest a combination of overlapping and unique patterns of cognitive impairment for children with ASD as compared to those with ADHD, particularly when the processes underlying reaction time measures are considered separately.

Indexed as

AdolescentAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildCognitive DysfunctionExecutive FunctionFemaleHumansMaleReaction TimeAttention-deficit/hyperactivity disorder (ADHD)Autism spectrum disorders (ASD)Diffusion modelExecutive functionNeuropsychologyReaction time variability

Identifiers

PMID29450820
PMCPMC6093794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.