Evidence map›Paper›PMID 29450698›Full record

ArticleWorld journal of surgery2018

Validation of the Japanese Version of the Low Anterior Resection Syndrome Score.

Emi Akizuki, Hiroshi Matsuno, Tetsuta Satoyoshi, Masayuki Ishii, Akihiro Usui, Tomomi Ueki, Toshihiko Nishidate, Kenji Okita, Tsunekazu Mizushima, Masaki Mori and 1 more

Abstract readValidation Study
In one paragraph

Article in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  2. Article
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  7. Diagnosis and Treatment of Low Anterior Resection Syndrome.Journal of the anus, rectum and colon · 2025
    Review
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  12. Article
  13. Review
  14. Observational
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  18. Validation of the low anterior resection syndrome score in finnish patients: preliminary results on quality of life in different lars severity groups.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emi AkizukiDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Hiroshi MatsunoDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Tetsuta SatoyoshiDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Masayuki IshiiDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Akihiro UsuiDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Tomomi UekiDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Toshihiko NishidateDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Kenji OkitaDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan.
Tsunekazu MizushimaDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Masaki MoriDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Ichiro TakemasaDepartment of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan. itakemasa@sapmed.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe low anterior resection syndrome (LARS) score is a patient-reported outcome measure to evaluate the severity of bowel dysfunction after rectal cancer surgery by scoring the major symptoms of LARS. The aim of this study was to translate the English version of the LARS score into Japanese and to investigate the validity and reliability of the LARS score.

methodsThe LARS score was translated in Japanese following current international recommendations. A total of 149 rectal cancer patients completed the LARS score questionnaire and were also asked a single question assessing the impact of bowel function on quality of life (QoL). A total of 136 patients answered the LARS score questionnaire twice.

resultsThe Japanese LARS score showed high convergent validity, based on its good correlation between the LARS score and QoL (p < 0.001). The LARS score was able to discriminate between patients according to the tumor distance to anal verge (p < 0.001), type of surgery (p < 0.001), and time since surgery (p = 0.001). Patients after ultra-low anterior resection and intersphincteric resection showed especially high scores. The score also had high test-retest reliability (intraclass correlation coefficient: 0.87).

conclusionThe Japanese LARS score is a valid and reliable tool for measuring LARS. The LARS score is appropriate for assessments in postoperative bowel function and international comparison. Using this score, patient-reported outcome measures of LARS in Japanese patients can be shared internationally. Additional validation reports from non-English speaking countries can support the LARS score as a worldwide assessment tool for postoperative bowel dysfunction.

Indexed as

Patient Outcome AssessmentQuality of LifeAdultAgedDefecationDigestive System Surgical ProceduresFemaleHumansMaleMiddle AgedRectal NeoplasmsRectumReproducibility of ResultsSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID29450698
PMCPMC6060820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.