Observational studySurgical endoscopy2018
Preoperative combination of progressive pneumoperitoneum and botulinum toxin type A in patients with loss of domain hernia.
Observational study in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Effect of preoperative botulinum toxin injection in the treatment of giant incisional hernias: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Systematic review and meta-analysis of the pre-operative application of botulinum toxin for ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2023Pooled it
- A systematic review of the use of progressive preoperative pneumoperitoneum since its inception.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- What Exactly is Meant by "Loss of Domain" for Ventral Hernia? Systematic Review of Definitions.World journal of surgery · 2019Pooled it
- From pixels to prediction: CT morphometrics and artificial intelligence in complex ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2026Review
- A practical algorithm for the combined use of preoperative progressive pneumoperitoneum and botulinum toxin A in large incisional hernia repair: learnings after 15 years of experience.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Ultrasound-Guided Botulinum Toxin A as an Adjunct to Intraoperative Fascial Traction in Incisional Hernia Repair: Registry-Based Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Loss of domain incisional hernia: challenges simplified by standardizing the use of botulinum toxin A and preoperative progressive pneumoperitoneum.Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- Ultrasound alone is sufficient: no added value of electromyography in botulinum toxin prehabilitation for complex ventral hernias?Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- Multimodal Prehabilitation for Hernia Repair: Linking Metabolic Modulation and Mechanical Methods.Biomedicines · 2025Review
- A Preoperative Algorithm for Loss of Domain Hernia Repair: Stratified Management Using the Tanaka Index in 50 Cases.Journal of abdominal wall surgery : JAWS · 2025Article
- Complications related to the prehabilitation with preoperative pneumoperitoneum in loss of domain hernias: our experience in 180 consecutive cases.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- Volumetry after botulinum toxin A: the impact on abdominal wall compliance and endotracheal pressure.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- [Loss of domain and reduction in median suture tension].Chirurgie (Heidelberg, Germany) · 2024Review
- Simultaneous stoma closure and type IV parastomal hernia repair after botulinum toxin and progressive pneumoperitoneum.Journal of surgical case reports · 2023Article
- Robotic-assisted repair of incisional hernia-early experiences of a university robotic hernia program and comparison with open and minimally invasive sublay technique (eMILOS).Langenbeck's archives of surgery · 2023Article
- A Systematic Review of Fibonacci Sequence in the Human Abdominal Wall: Facts and Reality.Cureus · 2022Review
- Accidental peritoneum-cutaneous fistula after insufflation of preoperative progressive pneumoperitoneum in a large incisional hernia with loss of domain.BMJ case reports · 2022Article
- Editorial: Botox in Complex Abdominal Wall Surgery.Frontiers in surgery · 2022Article
- Preoperative botulinum A toxin as an adjunct for abdominal wall reconstruction: a single-center early experience at an Academic Center in New York.Revista do Colegio Brasileiro de Cirurgioes · 2022Observational
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPreoperative progressive pneumoperitoneum (PPP) and botulinum toxin type A (BT) are tools in the surgical preparation of patients with loss of domain hernias (LODH). The aim of this paper is to report our experience with these preoperative techniques in 70 patients with LODH.
methodsObservational study of 70 consecutive patients with LODH was conducted between May 2010 and May 2016. Diameters of the hernia sac, incisional hernia (VIH), and abdominal cavity (VAC) volumes, and VIH/VAC ratio were measured before and after PPP and BT, using abdominal CT scan data. Combination of both techniques was performed when the VIH/VAC ratio was > 20%.
resultsMedian insufflated volume of air for PPP was 8450 ± 3400 cc (4500-13,450), over a period of 11.3 ± 2.3 days (9-16). BT administration time was 38.1 ± 3.7 days (35-44). An average reduction of 16.6% of the VIH/VAC ratio after PPP and BT was obtained (p < 0.05). Complications associated with PPP were 20%, and with surgical technique 29.6%. No complications occurred during the BT administration. Reconstructive technique was anterior CST in 54 patients, TAR in 14 cases and Rives-Stoppa technique in two patients. Median follow-up was 34.5 ± 22.3 months (12-60) and four cases of hernia recurrence (5.7%) were reported.
conclusionsUsing a CT volumetric protocol, combination of PPP and BT decreases the VIH/VAC ratio and hernia defect diameters, which constitutes a key factor in the treatment of LODH.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.