Observational studyJAMA surgery2018
Incidence of Delayed Intracranial Hemorrhage in Older Patients After Blunt Head Trauma.
Observational study in JAMA surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department With Mild Traumatic Brain Injury: Approved by ACEP Board of Directors, February 1, 2023 Clinical Policy Endorsed by the Emergency Nurses Association (April 5, 2023).Annals of emergency medicine · 2023Guideline
- Incidence of delayed bleeding in patients on antiplatelet therapy after mild traumatic brain injury: a systematic review and meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- Delayed Intracranial Hemorrhage after Blunt Head Trauma while on Direct Oral Anticoagulant: Systematic Review and Meta-Analysis.Journal of the American College of Surgeons · 2021Pooled it
- Predicting Progression of Intracranial Hemorrhage in the Prehospital TXA for TBI Trial.Journal of neurotrauma · 2024Trial
- Is a Repeat Head CT Scan Necessary After an Initial Negative Scan in Head Trauma Patients on DOAC Therapy in the Emergency Department?Journal of clinical medicine · 2026Article
- Minimal head injury in asymptomatic patients on antithrombotic therapy: is in-hospital observation justified after an initial normal computed tomography scan?Internal and emergency medicine · 2026Article
- Chinese expert consensus on the prehospital management of major trauma.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026Article
- Factors Associated with Delayed Intracranial Hemorrhage in Trauma Patients : A Retrospective Study at a Level I Trauma Center.Journal of Korean Neurosurgical Society · 2026Article
- Factors Associated with Emergency Department Discharge After Falls in Residential Aged Care Facilities: A Rural Australian Observational Study.Journal of clinical medicine · 2025Article
- Article
- Incidence and outcomes of delayed intracranial hemorrhage: a population-based cohort study.Scientific reports · 2024Article
- The prevalence of clinically relevant delayed intracranial hemorrhage in head trauma patients treated with oral anticoagulants is very low: a retrospective cohort register study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Incidence of surgically treated chronic subdural hematoma after head injury with normal initial computed tomography.Acta neurochirurgica · 2024Article
- Impact of antithrombotic therapy on acute and delayed intracranial haemorrhage and evaluation of the need of short-term hospitalisation based on CT findings after mild traumatic brain injury: experience from an oral and maxillofacial surgery unit.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Observational
- Delayed intracranial hemorrhage after head trauma seems rare and rarely needs intervention-even in antiplatelet or anticoagulation therapy.International journal of emergency medicine · 2023Article
- Clinical Indicators for Primary Cranial CT Imaging after Mild Traumatic Brain Injury-A Retrospective Analysis.Journal of clinical medicine · 2023Article
- Process improvement using telemedicine consultation to prevent unnecessary interfacility transfers for low-severity blunt head trauma.BMJ open quality · 2023Article
- Mild Head Trauma (MHT) and Antiplatelet Therapy. Reply to Lorenzati et al. Comment on "Savioli et al. Mild Head Trauma: Is Antiplatelet Therapy a Risk Factor for Hemorrhagic Complications?Medicina (Kaunas, Lithuania) · 2021Article
- Challenges in the PREHOSPITAL emergency management of geriatric trauma patients - a scoping review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Article
- Computed tomography features of spontaneous acute intracranial hemorrhages in a tertiary hospital in Southern Ghana.The Pan African medical journal · 2021Article
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6 authors at 2 institutions in 1 country.
Funding
Abstract
Importance: Current guidelines conflict on the management of older adults who have blunt head trauma taking anticoagulant and antiplatelet medications. This is partially due to the limited data comparing patients who are taking these medications with those who are not. Objective: To investigate the incidence of delayed traumatic intracranial hemorrhage in older adults with head trauma, including those taking anticoagulant and antiplatelet medications. Design, Setting, and Participants: This prospective observational cohort study included patients 55 years and older who had blunt head trauma and were transported via emergency medical services between August 1, 2015, and September 30, 2016. The setting was a multicenter study conducted at 11 hospitals in northern California. Patients were excluded if they had traumatic intracranial hemorrhage on the initial cranial computed tomographic scan, did not have a cranial computed tomographic scan performed at the initial emergency department visit, refused consent for a follow-up telephone call, or did not have reliable means of follow-up. Main Outcome and Measure: The primary outcome of this study was the incidence of delayed traumatic intracranial hemorrhage within 14 days of injury. Results: Among 859 patients enrolled in the study, the median age was 75 years (interquartile range, 64-85 years), and 389 (45.3%) were male. A total of 343 patients (39.9%) were taking an anticoagulant or antiplatelet medication. Three patients (0.3%; 95% CI, 0.1%-1.0%) had a delayed traumatic intracranial hemorrhage. Of the 3 patients, 1 of 75 patients (1.3%; 95% CI, 0.0%-7.2%) who were taking warfarin sodium alone and 2 of 516 patients (0.4%; 95% CI, 0.1%-1.4%) who were not taking any anticoagulant or antiplatelet medication had a delayed traumatic intracranial hemorrhage. Thirty-nine patients (4.5%; 95% CI, 3.2%-6.2%) were lost to follow-up. Conclusions and Relevance: Overall, the incidence of delayed intracranial hemorrhage in older adults who have blunt head trauma is low, including patients taking an anticoagulant or antiplatelet medication. These findings suggest that routine observation and serial cranial computed tomography may not be necessary in these patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.