Evidence map›Paper›PMID 29450364›Full record

ReviewRomanian journal of ophthalmology

Matrix regenerative therapy.

Cristina-Mihaela Timaru, Cornel Stefan, Daniela Adriana Iliescu, Algerino De Simone, Mehdi Batras

Abstract readReview
In one paragraph

Review in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Matrix regenerative therapy.Romanian journal of ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina-Mihaela Timaruphthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Cornel Stefanphthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Daniela Adriana Iliescuphthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Algerino De Simonephthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.
Mehdi Batrasphthalmology Department, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix (ECM) is responsible for many of the cell behavior processes, including cell proliferation and growth, survival, change in cell shape, migration, and differentiation. The most important component of the ECM is heparan sulfate (HS), because it insures the storage of many cell communication proteins, necessary for the continuous and identical renewal of cells and thus for tissue regeneration. Regenerating agents (RGTA®) are bioengineered structural analogues of heparan sulfate glycosaminoglycans that replace the degraded endogenous HS of the ECM. In the ophthalmological field, RGTA® represents an innovative approach for the improvement of the ocular surface wound healing and matrix remodeling and plays a role in controlling and regulating the wound healing process in various ocular diseases.

Indexed as

Biomimetic MaterialsCell- and Tissue-Based TherapyCorneal DiseasesExtracellular MatrixGuided Tissue RegenerationHeparan SulfateHumansRegenerative MedicineTissue EngineeringWound HealingHeparan Sulfateextracellular matrixregenerating agentsRGTAwound healing

Identifiers

PMID29450364
PMCPMC5710048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.