Fulminant bilateral acute retinal necrosis after chickenpox - a case report.

Ana Maria Dascalu, Daniela Stana, Alina Popa-Cherecheanu, Matei Popa-Cherecheanu, Dragos Serban

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Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact, top 68% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ana Maria Dascalu"Carol Davila" University of Medicine and Pharmacy, Bucharest.

Daniela StanaOphthalmology Department, University Emergency Hospital, Bucharest.

Alina Popa-Cherecheanu"Carol Davila" University of Medicine and Pharmacy, Bucharest.

Matei Popa-Cherecheanu"Prof. Agrippa Ionescu" Emergency Hospital, Balotesti.

Dragos Serban"Carol Davila" University of Medicine and Pharmacy, Bucharest.

Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 34-year-old male, admitted for progressive bilateral loss of vision after a recent episode of chickenpox. Ophthalmological exam revealed bilateral acute retinal necrosis. As the patient was following a drug detoxification program, he was tested for HIV, HVB, HVC, and results highly positive. Immediate intravenous therapy with high doses of acyclovir and methylprednisolone was initiated, but the evolution was extremely severe resulting in necrotic retinal detachment. Surgery was performed in right eye, but no improvement of visual acuity was observed.

conclusionsThe fulminant evolution of bilateral acute retinal necrosis and the lack of response to maximal intravenous therapy were clinical elements indicating coexistent immunosuppressive disease. Very severe acute retinal necrosis may occur in immunosuppressed patients, leading to blindness.

Indexed as

AdultAntiviral AgentsChickenpoxDexamethasoneEye Infections, ViralHepatitis BHepatitis CHIV InfectionsHumansMaleRetinal Necrosis Syndrome, AcuteAntiviral AgentsDexamethasoneacute retinal necrosisHIVintravenous drug addictionvaricellaviral opportunistic infections

Identifiers

PMID29450346

PMCPMC5720133

OpenAlexW3024897323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.