Evidence map›Paper›PMID 29450242›Full record

ArticleAddictive behaviors reports2017

One-year abstinence improves ADHD symptoms among patients with polysubstance use disorder.

Egon Hagen, Aleksander H Erga, Sverre M Nesvåg, James R McKay, Astri J Lundervold, Espen Walderhaug

Open access · goldAbstract read
In one paragraph

Article in Addictive behaviors reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Egon HagenKORFOR - Center for Alcohol and Drug Research, Stavanger University Hospital, PB 8100, 4068 Stavanger, Norway.
Aleksander H ErgaThe Norwegian Centre for Movement Disorders, Stavanger University Hospital, PB 8100, 4068 Stavanger, Norway.
Sverre M NesvågKORFOR - Center for Alcohol and Drug Research, Stavanger University Hospital, PB 8100, 4068 Stavanger, Norway.
James R McKayPerelman School of Medicine, Department of Psychiatry, University of Pennsylvania, 3440 Market St., Suite 370, Philadelphia, PA 19104, USA.
Astri J LundervoldDepartment of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
Espen WalderhaugDepartment of Addiction Treatment, Oslo University Hospital, Gaustad, PB 4956, 0424 Oslo, Norway.
Stavanger University Hospital · NOOslo University Hospital · NOUniversity of Bergen · NOUniversity of Pennsylvania · US

Funding

Adaptive Treatment Models for the Management of Drug Use DisordersK24DA029062 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI MCKAY, JAMES R. · 2010 to 2021
$1.6M
NIDA NIH HHS K24 DA029062
6 · The paper itself

Abstract

introductionAttention-deficit/hyperactivity disorder (ADHD) is a common comorbid disorder in patients suffering from substance use disorder (SUD). Individuals with co-occurring SUD and ADHD are more likely than SUD patients without ADHD to have developed SUD at a younger age, be polysubstance users, and need inpatient treatment more often. The present study investigates whether individuals with polysubstance use disorder who remain abstinent for a year after entering treatment have a more substantial reduction in ADHD symptoms than those who relapsed and controls. MATERIAL AND

methodsSubjects were SUD patients (N = 115) and healthy controls (N = 34). ADHD symptoms were assessed using the adult ADHD Self-Report Scale (ASRS). Substance use was assessed by self-reports on the Alcohol Use Disorders Identification Test (AUDIT) and the Drug Use Disorders Identification Test (DUDIT). Participants were defined as having relapsed if they had an AUDIT score ≥ 8 or a DUDIT score ≥ 2 for women and ≥ 6 for men.

resultsPatients who remained abstinent for one year reported a substantial reduction of ADHD symptoms compared to patients who relapsed and controls.

conclusionsAbstinence alleviates ADHD symptoms among patients with polysubstance use disorder. We suggest that confirmation of an ADHD diagnosis should follow a period of abstinence to avoid identification of false-positive cases.

Indexed as

ADHDADHD, attention deficit hyperactivity disorderANOVA, analysis of varianceASRS, ADHD Self-Report ScaleAUDIT, Alcohol Use Disorders Identification TestDSM, Diagnostic and Statistical Manual of Mental DisordersDUDIT, Drug Use Disorders Identification TestGP, general practitionerPolysubstanceRecoveryREK, Regional Ethical CommitteeSubstance use disorderSUD, substance use disorderWASI, Wechsler abbreviated scale of intelligence

Identifiers

PMID29450242
PMCPMC5800580
OpenAlexW2751524273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.