Evidence map›Paper›PMID 29450132›Full record

ArticleBiochimie open2016

Green tea polyphenols affect invasiveness of human gastric MKN-28 cells by inhibition of LPS or TNF-α induced Matrix Metalloproteinase-9/2.

Rosaria Arcone, Margherita Palma, Valentina Pagliara, Giulia Graziani, Mariorosario Masullo, Gerardo Nardone

Open access · hybridAbstract read
In one paragraph

Article in Biochimie open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  6. Article
  7. Effect ofMolecules (Basel, Switzerland) · 2020
    Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rosaria ArconeDipartimento di Scienze Motorie e del Benessere, Università di Napoli "Parthenope", Via Medina 40, 80133 Napoli, Italy.
Margherita PalmaDipartimento di Medicina Clinica e Chirurgica, Università di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy.
Valentina PagliaraDipartimento di Scienze Motorie e del Benessere, Università di Napoli "Parthenope", Via Medina 40, 80133 Napoli, Italy.
Giulia GrazianiDipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy.
Mariorosario MasulloDipartimento di Scienze Motorie e del Benessere, Università di Napoli "Parthenope", Via Medina 40, 80133 Napoli, Italy.
Gerardo NardoneDipartimento di Medicina Clinica e Chirurgica, Università di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy.
Parthenope University of Naples · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies demonstrated a correlation between green tea consumption and a reduced cancer risk. Among different components, green tea polyphenols have been identified as molecules responsible for the beneficial effects showed by the green tea against oxidative stress and cell invasiveness. In this study, we investigated the effects of green tea polyphenol extracts (GTPs) in human gastric MKN-28 cell line. To this aim, we have first evaluated the effect of GTPs on oxidative stress induced cell injury. The pre-treatment with 10

Indexed as

Cell invasionCell migrationDMEM, Dulbecco's Modified Eagles's MediumDMSO, Dimethyl sulfoxideECM, Extracellular matrixFBS, fetal bovine serumGreen tea polyphenolsGTPs, Green tea polyphenols extractLPS, LipopolysaccharideMatrix Metalloproteinase-2 (MMP-2)Matrix Metalloproteinase-9 (MMP-9)MKN-28 gastric cancer cellsMMP-, Matrix metalloproteinasePBS, Phosphate-buffer salineROS, Reactive Oxygen SpeciesTNF-α, Tumor necrosis factor α

Identifiers

PMID29450132
PMCPMC5802102
OpenAlexW2549034508

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.