Evidence map›Paper›PMID 29449965›Full record

ArticleVirus evolution2018

Genetic diversity and cross-species transmission of kobuviruses in Vietnam.

Lu Lu, Nguyen Van Dung, Alasdair Ivens, Carlijn Bogaardt, Aine O'Toole, Juliet E Bryant, Juan Carrique-Mas, Nguyen Van Cuong, Pham Hong Anh, Maia A Rabaa and 6 more

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Identification of Aichivirus in a Pet Rat (Animals : an open access journal from MDPI · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Viruses · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Detection and molecular characterization of kobuvirus from diarrheic goats in Minnesota.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Lu LuAshworth Laboratories, Centre for Immunity, Infection and Evolution, University of Edinburgh, Kings Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Nguyen Van DungNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Alasdair IvensAshworth Laboratories, Centre for Immunity, Infection and Evolution, University of Edinburgh, Kings Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Carlijn BogaardtAshworth Laboratories, Centre for Immunity, Infection and Evolution, University of Edinburgh, Kings Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.ORCID 0000-0002-9322-6978
Aine O'TooleAshworth Laboratories, Centre for Immunity, Infection and Evolution, University of Edinburgh, Kings Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
Juliet E BryantNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Juan Carrique-MasNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Nguyen Van CuongThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 764 Vo Van Kiet, W.1, Dist. 5, Ho Chi Minh City, Vietnam.
Pham Hong AnhThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 764 Vo Van Kiet, W.1, Dist. 5, Ho Chi Minh City, Vietnam.
Maia A RabaaNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Ngo Tri TueThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 764 Vo Van Kiet, W.1, Dist. 5, Ho Chi Minh City, Vietnam.
Guy E ThwaitesNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Stephen BakerNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Peter SimmondsNuffield Department of Medicine, University of Oxford, South Parks Road, Oxford OX1 3SY, UK.
Mark Ej WoolhouseAshworth Laboratories, Centre for Immunity, Infection and Evolution, University of Edinburgh, Kings Buildings, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.
VIZIONS Consortium
University of Oxford · GBCentre for Immunity, Infection and Evolution · GBOxford University Clinical Research Unit · VNUniversity of Cambridge · GB

Funding

Wellcome Trust 110085/Z/15/Z
6 · The paper itself

Abstract

Cross-species transmission of viruses poses a sustained threat to public health. Due to increased contact between humans and other animal species the possibility exists for cross-species transmissions and ensuing disease outbreaks. By using conventional PCR amplification and next generation sequencing, we obtained 130 partial or full genome kobuvirus sequences from humans in a sentinel cohort in Vietnam and various mammalian hosts including bats, rodents, pigs, cats, and civets. The evolution of kobuviruses in different hosts was analysed using Bayesian phylogenetic methods. We estimated and compared time of origin of kobuviruses in different host orders; we also examined the cross-species transmission of kobuviruses within the same host order and between different host orders. Our data provide new knowledge of rodent and bat kobuviruses, which are most closely related to human kobuviruses. The novel bat kobuviruses isolated from bat roosts in Southern Vietnam were genetically distinct from previously described bat kobuviruses, but closely related to kobuviruses found in rodents. We additionally found evidence of frequent cross-species transmissions of kobuviruses within rodents. Overall, our phylogenetic analyses reveal multiple cross-species transmissions both within and among mammalian species, which increases our understanding of kobuviruses genetic diversity and the complexity of their evolutionary history.

Indexed as

Bayesian phylogeneticscross-species transmissionkobuvirusnext generation sequencing

Identifiers

PMID29449965
PMCPMC5810437
OpenAlexW2791107119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.