ArticleAnnals of general psychiatry2018
Off-label prescription of psychiatric drugs by non-psychiatrist physicians in three general hospitals in Germany.
Article in Annals of general psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Antipsychotic-induced motor symptoms in schizophrenic psychoses-Part 3 : Tardive dyskinesia].Der Nervenarzt · 2019Pooled it
- A prospective observational study on the off-label use of medications in the psychiatry outpatient department of a tertiary care hospital.Indian journal of pharmacology · 2026Observational
- Prevalence of Antidepressant Prescription in Adolescents Newly Diagnosed with Depression in Germany.Children (Basel, Switzerland) · 2024Article
- Knowledge and dispensing practice of community pharmacists towards antipsychotic medicines in a Nigerian metropolitan city - a cross-sectional study.BMC health services research · 2023Article
- The risk of hospitalization for psychotic disorders following hospitalization for COVID-19: a French nationwide longitudinal study.Molecular psychiatry · 2023Article
- A Medical Resident with a History of Alcohol Abuse and Suicidal Ideation: A Challenge for Both Psychiatry and Occupational Medicine in the Context of the First Wave of the COVID-19 Pandemic.Case reports in psychiatry · 2022Article
- GABAFrontiers in psychiatry · 2022Review
- Patterns and Predictors of Off-Label Drug Prescribing in Psychiatric Practice: A Qualitative Study.Pharmacy (Basel, Switzerland) · 2021Article
- Off-Label Medication: From a Simple Concept to Complex Practical Aspects.International journal of environmental research and public health · 2021Review
- Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role?British journal of clinical pharmacology · 2020Article
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8 authors.
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Abstract
backgroundOff-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic illness who were also suffering from a psychiatric pathology.
methodsUsing a prospective, observational design, we collected data from 982 hospitalized patients with a somatic illness for whom a psychiatric consultation was requested because of the presence of additional psychiatric symptoms. Data were collected at three hospitals in Germany. Demographic and clinical data, including the previous psychoactive medications and an assessment of the suitability of the previous medications, were recorded and analyzed.
resultsData on the previous psychiatric medications were available for 972 patients. In 16.6% of patients, at least one psychoactive drug had been prescribed off-label, 20.2% had received on-label medication, and 63.2% had not received any psychiatric medication. Among all patients receiving psychiatric medication, 45.1% had received off-label medication. The logistic regression analysis showed a significant influence of age on the likelihood of receiving off-label medication (
conclusionsOur data show a high frequency of the off-label prescription of psychoactive drugs by physicians treating patients with somatic illnesses in general hospitals. Because more than half of these cases were judged to be "not indicated", these prescriptions indicate a potential risk to patients. Furthermore, the classes of drugs that were most frequently prescribed off-label, benzodiazepines and antipsychotics, both show a substantial risk profile, particularly for elderly patients.
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