Evidence map›Paper›PMID 29449777›Full record

ArticleBiomarker insights2018

A Homogeneous Time-Resolved Fluorescence Immunoassay Method for the Measurement of Compound W.

Biao Huang, Huixin Yu, Jiandong Bao, Manda Zhang, William L Green, Sing-Yung Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarker insights, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Biao HuangResearch Department, Jiangsu Nuclear Medicine Research Laboratory and Jiangyuan Hospital, Wuxi, China.
Huixin YuResearch Department, Jiangsu Nuclear Medicine Research Laboratory and Jiangyuan Hospital, Wuxi, China.
Jiandong BaoResearch Department, Jiangsu Nuclear Medicine Research Laboratory and Jiangyuan Hospital, Wuxi, China.
Manda ZhangResearch Department, Jiangsu Nuclear Medicine Research Laboratory and Jiangyuan Hospital, Wuxi, China.
William L GreenDepartment of Medicine, University of Washington, Seattle, WA, USA.
Sing-Yung WuDivision of Nuclear Medicine and Medical Services, Department of Radiological Sciences, School of Medicine, UC Irvine Medical Center and VA Long Beach Healthcare System, Long Beach, CA, USA.
University of California, Irvine · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveUsing compound W (a 3,3'-diiodothyronine sulfate [T

methodPhotosensitive particles (donor beads) coated with compound W or T

resultsThe sensitivity of the method was 5 pg/mL, and the detection range was 5 to 10 000 pg/mL. The intra-assay coefficient of variation averages <10% with stable reproducibility.

conclusionsThe ICW-AlphaLISA shows good stability and high sensitivity and can measure a wide range of compound W levels in extracts of maternal serum samples. This may have clinical application to screen congenital hypothyroidism in utero.

Indexed as

compound WHomogeneous time-resolved fluorescence immunoassaypregnancythyroid hormone analogs

Identifiers

PMID29449777
PMCPMC5808953
OpenAlexW2793897612

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.